ethyl (3S)-3-phenylbutanoate

Base Information

• Chemical Name: ethyl (3S)-3-phenylbutanoate
• CAS No.: 1134-71-0
• Molecular Formula: C₁₂H₁₆O₂
• Molecular Weight: 192.258
• Mol file: 1134-71-0.mol

Synonyms:ethyl (3S)-3-phenylbutanoate

Chemical Property of ethyl (3S)-3-phenylbutanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl (3S)-3-phenylbutanoate

There total 131 articles about ethyl (3S)-3-phenylbutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

ethyl (E)-3-phenylbut-2-enoate (945-93-7,13979-22-1,1504-72-9) → ethyl (3R)-3-phenylbutanoate (1134-71-0,62690-29-3,148261-96-5,4179-10-6)

Guidance literature:

With (R)-(-)-DTBM-SEGPHOS; sodium phenoxide; poly(methylhydrosiloxane); copper carbide; In toluene; tert-butyl alcohol; for 3h; ultrasonication;

DOI:10.1002/anie.200503149

Reference yield: 99.0%

ethyl (E)-3-phenylbut-2-enoate (945-93-7,13979-22-1,1504-72-9) → ethyl (3S)-3-phenylbutanoate (1134-71-0)

Guidance literature:

With C₃₂H₁₂BF₂₄^(1-)*C₃₇H₅₆IrNO₂PSi⁽¹⁺⁾; hydrogen; In dichloromethane; at 20 ℃; for 2h; under 37503.8 Torr; enantioselective reaction; Inert atmosphere; Schlenk technique;

DOI:10.3762/bjoc.12.114

Reference yield: 95.0%

ethyl 3-phenylbut-2-enoate (1504-72-9,13979-22-1,945-93-7) → ethyl 3-phenylbutanoate (1134-71-0,4179-10-6,148261-96-5,62690-29-3)

Guidance literature:

With chloro(1,5-cyclooctadiene)rhodium(I) dimer; tetrahydroxydiboron; water; triethylamine; In tetrahydrofuran; at 30 ℃; for 12h; Schlenk technique; Inert atmosphere;

DOI:10.1002/ejoc.202000049

upstream raw materials:

ethyl (E)-3-phenylbut-2-enoate

ethanol

3-phenylbutyric acid

ethyl 3-phenylbut-2-enoate

Downstream raw materials:

3-methylindanone

3-phenylbutyric acid

α,α,γ-trimethylbenzenepropanol

3-Phenylbutyraldehyde