d-Methionine sulfone

Base Information

• Chemical Name: d-Methionine sulfone
• CAS No.: 41486-92-4
• Molecular Formula: C5H11 N O4 S
• Molecular Weight: 181.21
• Hs Code.: 2922499990
• UNII: KI3SDH8M6R
• Nikkaji Number: J231.706K
• Wikidata: Q27094681
• Mol file: 41486-92-4.mol

Synonyms:41486-92-4;d-methionine sulfone;H-D-Met(O2)-OH;(R)-2-Amino-4-(methylsulfonyl)butanoic acid;(2R)-2-amino-4-methylsulfonylbutanoic acid;Methionine sulfone, D-;KI3SDH8M6R;D-Methionine, S,S-dioxide;(2R)-2-amino-4-methanesulfonylbutanoic acid;(2R)-2-azaniumyl-4-methylsulfonylbutanoate;(R)-4-(Methylsulfonyl)-2-aminobutanoic acid;UNII-KI3SDH8M6R;SCHEMBL1527360;MFCD00066019;AKOS027327883;CS-0452265;F10886;EN300-1298391;rel-(2R)-2-amino-4-methanesulfonylbutanoic acid;EN300-28271324;Q27094681

Chemical Property of d-Methionine sulfone

Chemical Property:

• PSA: 105.84000
• LogP: 0.61410
• XLogP3: -3.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 181.04087901
• Heavy Atom Count: 11
• Complexity: 227

Purity/Quality:

98%Min ^*data from raw suppliers

H-D-Met(O2)-OH ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CS(=O)(=O)CCC(C(=O)O)N
• Isomeric SMILES: CS(=O)(=O)CC[C@H](C(=O)O)N

Technology Process of d-Methionine sulfone

There total 5 articles about d-Methionine sulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

D-methionine (348-67-4,26062-47-5,58576-49-1) → D-methionine sulfone (41486-92-4,1118-85-0)

Guidance literature:

With urea hydrogen peroxide adduct; In ethanol; at 20 ℃; for 0.25h;

DOI:10.1016/j.catcom.2020.105931

Reference yield:

N-formyl-D-methionine S,S-dioxide (98549-25-8) → D-methionine sulfone (41486-92-4,1118-85-0)

Guidance literature:

With hydrogenchloride;

Reference yield:

DL-methionine sulfone (820-10-0,1118-85-0) → D-methionine sulfone (41486-92-4,1118-85-0)

Guidance literature:

Multi-step reaction with 3 steps

2: brucine

3: aqueous HCl

With hydrogenchloride; brucine;

upstream raw materials:

N-formyl-D-methionine S,S-dioxide

D-methionine

DL-methionine sulfone

N-formyl-DL-methionine S,S-dioxide

Downstream raw materials:

(R)-4-Methanesulfonyl-2-(4-methoxy-benzenesulfonylamino)-butyric acid

(R)-2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-tert-butoxy-4-methanesulfonyl-butyramide

(R)-2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-4-methanesulfonyl-butyric acid tert-butyl ester

(R)-2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-4-methanesulfonyl-butyric acid