2-Nitroso-5-dimethylaminophenol Hydrochloride

Base Information

• Chemical Name: 2-Nitroso-5-dimethylaminophenol Hydrochloride
• CAS No.: 41317-10-6
• Molecular Formula: C8H10 N2 O2 . Cl H
• Molecular Weight: 202.641
• DSSTox Substance ID: DTXSID90431167
• Mol file: 41317-10-6.mol

Synonyms:41317-10-6;2-Nitroso-5-dimethylaminophenol Hydrochloride;5-Dimethylamino-2-nitrosophenol Hydrochloride;5-(dimethylamino)-2-nitrosophenol hydrochloride;2-Nitroso-5-dimethylaminophenol HCl;5-(dimethylamino)-2-nitrosophenol;hydrochloride;SCHEMBL104308;DTXSID90431167;MFCD00060162;AKOS015845823;SB77815;BS-22945;5-DIMETHYLAMINO-2-NITROSOPHENOL HCL;FT-0639707;N0261;5-(dimethylamino)-2-nitrosophenolhydrochloride;T72444;A825513;5-(Dimethylamino)-2-nitrosophenol--hydrogen chloride (1/1)

Chemical Property of 2-Nitroso-5-dimethylaminophenol Hydrochloride

Chemical Property:

• Vapor Pressure: 5.29E-05mmHg at 25°C
• Boiling Point: 337.6°C at 760 mmHg
• Flash Point: 158°C
• PSA: 52.90000
• LogP: 2.65810
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly, Heated, Sonicated), Methanol (Slightly), Water (Slightly)
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 202.0509053
• Heavy Atom Count: 13
• Complexity: 161

Purity/Quality:

97% ^*data from raw suppliers

2-nitroso-5-dimethylaminophenolhydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CN(C)C1=CC(=C(C=C1)N=O)O.Cl

Technology Process of 2-Nitroso-5-dimethylaminophenol Hydrochloride

There total 1 articles about 2-Nitroso-5-dimethylaminophenol Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

3-Dimethylaminophenol (99-07-0) → 2-nitroso-5-dimethylaminophenol hydrochloride (41317-10-6)

Guidance literature:

With hydrogenchloride; sodium nitrite; In water; at 5 ℃; for 2h;

Reference yield:

2-nitroso-5-dimethylaminophenol hydrochloride (41317-10-6) → 2-amino-5-(dimethylamino)phenol (15103-39-6)

Guidance literature:

With sodium dithionite; basic medium;

DOI:10.1246/bcsj.60.2657

Reference yield:

2-nitroso-5-dimethylaminophenol hydrochloride (41317-10-6) → 7-dimethylamino-3-phenyl-2H-1,4-benzoxazin-2-one (92510-34-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium dithionite / basic medium

2: 40 percent / toluene / 1 h / Heating

With sodium dithionite; In toluene;

DOI:10.1246/bcsj.60.2657

upstream raw materials:

3-Dimethylaminophenol

Downstream raw materials:

2-amino-5-(dimethylamino)phenol

7-dimethylamino-3-phenyl-2H-1,4-benzoxazin-2-one