15103-39-6Relevant articles and documents
Fluorescent chemodosimeter for Cys/Hcy with a large absorption shift and imaging in living cells
Hu, Mingming,Fan, Jiangli,Li, Honglin,Song, Kedong,Wang, Song,Cheng, Guanghui,Peng, Xiaojun
, p. 980 - 983 (2011)
A novel molecule T1 with efficient intramolecular charge transfer was designed as a fluorescent chemodosimeter for cysteine (Cys) and homocysteine (Hcy). Upon addition of Cys/Hcy, T1 exhibited greatly enhanced fluorescence intensity as well as a large absorption peak shift (70 nm), and can be used for bioimaging of Cys/Hcy in living cells and detection in human plasma by visual color change. The detection mechanism was proved by 1H NMR, mass spectrometry analysis and Gaussian calculations.
A fluorescent probe for bisulfite ions: its application to two-photon tissue imaging
Agarwalla, Hridesh,Pal, Suman,Paul, Anirban,Jun, Yong Woong,Bae, Juryang,Ahn, Kyo Han,Srivastava, Divesh N.,Das, Amitava
, p. 7888 - 7894 (2016/12/16)
A benzoxazinone based fluorescent probe for the specific and efficient detection of bisulfite ions in aqueous medium is described. The probe formed a bisulfite/sulphite adduct with an associated turn-on fluorescence response in the red wavelength region. No interference was observed in the detection process from all possible competing anions and molecules, including cyanide ion, cysteine, homocysteine and glutathione. In addition, the probe showed a fast response time, low detection limit, and cell membrane permeability. Furthermore, the probe was two-photon excitable, enabling imaging of endogenous bisulfite ions in HeLa cells as well as in deep tissues from different organs of mouse.
LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES
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Page/Page column 21; 44, (2008/06/13)
Reactive fluorescent dyes compositions and methods of using same are disclosed. Squaraine nucleus, Nile red nucleus, benzodioxazole nucleus, coumarin nucleus or aza coumarin nucleus dyes are disclosed dyes are disclosed having thiol-reactive groups. Squaraine nucleus, Nile Red nucleus, benzodioxazole nucleus, coumarin nucleus or aza coumarin nucleus dyes are disclosed that exhibit a fluorescence emission of at least about 575 nm. Biosensors are disclosed having a binding protein and a squaraine nucleus, Nile Red nucleus, benzodiaxazole nucleus, coumarin nucleus or aza coumarin nucleus.