1-PHENYL-2-PIPERAZIN-1-YLETHANONE DIHYDROCHLORIDE

Base Information

• Chemical Name: 1-PHENYL-2-PIPERAZIN-1-YLETHANONE DIHYDROCHLORIDE
• CAS No.: 41298-98-0
• Molecular Formula: C12H16 N2 O
• Molecular Weight: 204.27
• Hs Code.: 2933599090
• Mol file: 41298-98-0.mol

Synonyms:1-Phenacylpiperazine

Chemical Property of 1-PHENYL-2-PIPERAZIN-1-YLETHANONE DIHYDROCHLORIDE

Chemical Property:

• Boiling Point: 346.7±27.0 °C(Predicted)
• PKA: 8.95±0.10(Predicted)
• PSA: 32.34000
• Density: 1.072±0.06 g/cm3(Predicted)
• LogP: 2.64520

Purity/Quality:

98%Min ^*data from raw suppliers

1-Phenyl-2-(piperazin-1-yl)ethanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-PHENYL-2-PIPERAZIN-1-YLETHANONE DIHYDROCHLORIDE

There total 3 articles about 1-PHENYL-2-PIPERAZIN-1-YLETHANONE DIHYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C13H16N2O2 (109618-56-6) → 1-benzoylmethylpiperazine (41298-98-0)

Guidance literature:

C₁₃H₁₆N₂O₂; With sodium hydroxide; water; for 10h; Heating / reflux;

With hydrogenchloride; In water; pH=8;

Reference yield:

piperazine (110-85-0) + α-bromoacetophenone (70-11-1) → 1-benzoylmethylpiperazine (41298-98-0)

Guidance literature:

In acetonitrile; Reflux;

Reference yield:

→ 1-benzoylmethylpiperazine (41298-98-0)

Guidance literature:

1) N-Monoformylpiperazin, ω-Bromacetophenon, 95percent-Ethanol, Erwaermung 2) Behandlung mit Salzsaeure unter Erwaermung;

upstream raw materials:

C₁₃H₁₆N₂O₂

piperazine

α-bromoacetophenone

Downstream raw materials:

1-[[3-Methoxy-4-(methylaminocarbonyloxy)phenyl]methyl]-4-(4-acetylphenyl)piperazine

N-(5,11-Dihydro-10-thia-dibenzo[a,d]cyclohepten-5-yl)-4-[4-(2-oxo-2-phenyl-ethyl)-piperazin-1-yl]-butyramide

Refernces

• 1、 -. "Aralkyl-ketone piperazine derivatives and their uses as new antalgic or ataractic agent". Page/Page column 8. . Retrieved 2008/06/13.