(3S,4R,5R)-4,5-Dihydroxyhexahydropyridazine-3-carboxylic acid

Base Information

Chemical Name:(3S,4R,5R)-4,5-Dihydroxyhexahydropyridazine-3-carboxylic acid
CAS No.:443649-22-7
Molecular Formula:C₅H₁₀N₂O₄
Molecular Weight:162.145
Hs Code.:
DSSTox Substance ID:DTXSID20438826
Nikkaji Number:J1.691.940C
Wikidata:Q82254658
Mol file:443649-22-7.mol

Synonyms:443649-22-7;(3S,4R,5R)-4,5-Dihydroxyhexahydropyridazine-3-carboxylic acid;Azaglucuronofagomine;DTXSID20438826;(3S,4R,5R)-4,5-Dihydroxyhexahydropyridazine-3-carboxylicacid

Suppliers and Price of (3S,4R,5R)-4,5-Dihydroxyhexahydropyridazine-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (3S,4R,5R)-4,5-Dihydroxyhexahydropyridazine-3-carboxylic acid

Chemical Property:

PSA：0.00000
LogP:0.00000
XLogP3:-4
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:162.06405680
Heavy Atom Count:11
Complexity:163

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(C(C(NN1)C(=O)O)O)O
Isomeric SMILES:C1[C@H]([C@@H]([C@H](NN1)C(=O)O)O)O

Technology Process of (3S,4R,5R)-4,5-Dihydroxyhexahydropyridazine-3-carboxylic acid

There total 3 articles about (3S,4R,5R)-4,5-Dihydroxyhexahydropyridazine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 449146-84-3
(3R,4R,5R)-1,2-diacetyl-4,5-dibenzyloxy-3-hydroxymethylhexahydropyridazine

: 443649-22-7
(3S,4R,5R)-4,5-dihydroxyhexahydropyridazine-3-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 66 percent / CrO₃; sulfuric acid / acetone / 0 °C

2: H₂; aq. HCl / 10percent Pd/C / methanol / 2 h / 20 °C / 760.05 Torr

3: 30 mg / aq. HCl / 24 h / 100 °C

With chromium(VI) oxide; hydrogenchloride; sulfuric acid; hydrogen; 10percent Pd/C; In methanol; acetone; 1: Jones oxidation;
DOI:10.1039/b200884j

Reference yield:

: 449146-86-5
(3S,4R,5R)-1,2-diacetyl-4,5-dibenzyloxyhexahydropyridazine-3-carboxylic acid

: 443649-22-7
(3S,4R,5R)-4,5-dihydroxyhexahydropyridazine-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: H₂; aq. HCl / 10percent Pd/C / methanol / 2 h / 20 °C / 760.05 Torr

2: 30 mg / aq. HCl / 24 h / 100 °C

With hydrogenchloride; hydrogen; 10percent Pd/C; In methanol;
DOI:10.1039/b200884j