ethyl 1-(chloromethyl)-1,2,3,6-tetrahydro-4-methyl-2-oxo-6-phenylpyrimidine-5-carboxylate

Base Information

• Chemical Name: ethyl 1-(chloromethyl)-1,2,3,6-tetrahydro-4-methyl-2-oxo-6-phenylpyrimidine-5-carboxylate
• CAS No.: 1361315-27-6
• Molecular Formula: C₁₅H₁₇ClN₂O₃
• Molecular Weight: 308.765

Synonyms:ethyl 1-(chloromethyl)-1,2,3,6-tetrahydro-4-methyl-2-oxo-6-phenylpyrimidine-5-carboxylate

Chemical Property of ethyl 1-(chloromethyl)-1,2,3,6-tetrahydro-4-methyl-2-oxo-6-phenylpyrimidine-5-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 1-(chloromethyl)-1,2,3,6-tetrahydro-4-methyl-2-oxo-6-phenylpyrimidine-5-carboxylate

There total 1 articles about ethyl 1-(chloromethyl)-1,2,3,6-tetrahydro-4-methyl-2-oxo-6-phenylpyrimidine-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + ethyl 6-methyl-4-phenyl-3,4-dihydropyrimidin-2(1H)-one-5-carboxylate (123237-03-6,5395-36-8) → ethyl 1-(chloromethyl)-1,2,3,6-tetrahydro-4-methyl-2-oxo-6-phenylpyrimidine-5-carboxylate (1361315-27-6)

Guidance literature:

With chloro-trimethyl-silane; In dichloromethane; at 40 ℃; for 24h; regioselective reaction;

DOI:10.2174/157017811795038458

Reference yield:

syn-benzaldehyde oxime (932-90-1,622-31-1,140461-24-1,140461-25-2,622-32-2) + ethyl 1-(chloromethyl)-1,2,3,6-tetrahydro-4-methyl-2-oxo-6-phenylpyrimidine-5-carboxylate (1361315-27-6) → ethyl 3-[({(E)-benzylideneamino}oxy)methyl]-6-methyl-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate (1426902-88-6)

Guidance literature:

With triethylamine; In dichloromethane; at 40 ℃; for 12h;

DOI:10.3184/174751912X13546462577913

Reference yield:

ortho-methylbenzoic acid (118-90-1) + ethyl 1-(chloromethyl)-1,2,3,6-tetrahydro-4-methyl-2-oxo-6-phenylpyrimidine-5-carboxylate (1361315-27-6) → C23H24N2O5 (1307308-42-4)

Guidance literature:

With triethylamine; potassium iodide; In dichloromethane; at 40 ℃; for 6h;

DOI:10.2174/157017811795038458

upstream raw materials:

formaldehyd

ethyl 6-methyl-4-phenyl-3,4-dihydropyrimidin-2(1H)-one-5-carboxylate

Downstream raw materials:

C₂₃H₂₄N₂O₅

C₂₂H₂₁BrN₂O₅

5-ethoxycarbonyl-6-methyl-3-benzoyl-4-phenyl-3,4-dihydropyrimidin-2(1H)-one

C₁₇H₂₀N₂O₅

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1361315-27-6 ethyl 1-(chloromethyl)-1,2,3,6-tetrahydro-4-methyl-2-oxo-6-phenylpyrimidine-5-carboxylate

Send

Send

Metric Ton KG G Pound L ML

Send

Send