Technology Process of C15H16F4N2O2
There total 2 articles about C15H16F4N2O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
triethylamine;
In
methanol;
at 20 ℃;
for 4h;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / ethyl acetate / 3 h / 20 °C / Reflux
1.2: 1.5 h / 20 °C
2.1: sodium hypochlorite / dichloromethane; water / 0.5 h / 20 °C
3.1: n-butyllithium / toluene; hexane; tetrahydrofuran / 0.5 h / -70 °C / Inert atmosphere
3.2: 0.42 h / -70 °C / Inert atmosphere
3.3: 1.25 h / -70 °C / Inert atmosphere
4.1: nitric acid; sulfuric acid / 1 h / Cooling with ice
5.1: ammonium chloride; iron / ethanol; water / 2 h / 20 - 45 °C
6.1: triethylamine / methanol / 4 h / 20 °C
With
sodium hypochlorite; n-butyllithium; sulfuric acid; nitric acid; iron; ammonium chloride; triethylamine; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione;
In
tetrahydrofuran; methanol; ethanol; hexane; dichloromethane; water; ethyl acetate; toluene;
- Guidance literature:
-
With
hydrogen;
5% rhodium-on-charcoal;
In
ethanol;
at 20 ℃;
for 23h;