C₃₇H₄₂O₄

Base Information

• Chemical Name: C₃₇H₄₂O₄
• CAS No.: 351885-69-3
• Molecular Formula: C₃₇H₄₂O₄
• Molecular Weight: 550.738
• Mol file: 351885-69-3.mol

Synonyms:C₃₇H₄₂O₄

Chemical Property of C₃₇H₄₂O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₇H₄₂O₄

There total 4 articles about C₃₇H₄₂O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

cyclopenta-1,3-diene (542-92-7,25568-84-7,7313-32-8) + (E)-3-[(1R,3S)-3-((E)-2-Phenethyloxycarbonyl-vinyl)-cyclopentyl]-acrylic acid phenethyl ester (522617-85-2) → C37H42O4 (351885-69-3)

Guidance literature:

With aluminium trichloride; trimethylaluminum; In dichloromethane; at 4 ℃;

DOI:10.1021/ja003712y

Reference yield:

norborn-2-ene (498-66-8) → C37H42O4 (351885-69-3)

Guidance literature:

Multi-step reaction with 4 steps

1.1: aq. K₃Fe(CN)6; K₂OsO₄; quinuclidine / K₂CO₃ / 2-methyl-propan-2-ol

2.1: aq. NaIO₄ / tetrahydrofuran / 0 - 20 °C

3.1: t-BuOK / tetrahydrofuran / 2 h / 0 - 20 °C

3.2: 90 percent / tetrahydrofuran / -78 - 4 °C

4.1: 87 percent / (CH₃)3Al; AlCl₃ / CH₂Cl₂ / 4 °C

With Quinuclidine; potassium osmate(VI); sodium periodate; aluminium trichloride; potassium tert-butylate; trimethylaluminum; potassium hexacyanoferrate(III); potassium carbonate; In tetrahydrofuran; dichloromethane; tert-butyl alcohol; 1.1: Sharpless dihydroxylation / 3.2: Horner-Wadsworth-Emmons reaction / 4.1: Diels-Alder cycloaddition;

DOI:10.1021/ja003712y

Reference yield:

cis-cyclopentane-1,3-dicarboxaldehyde (10283-91-7) → C37H42O4 (351885-69-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: t-BuOK / tetrahydrofuran / 2 h / 0 - 20 °C

1.2: 90 percent / tetrahydrofuran / -78 - 4 °C

2.1: 87 percent / (CH₃)3Al; AlCl₃ / CH₂Cl₂ / 4 °C

With aluminium trichloride; potassium tert-butylate; trimethylaluminum; In tetrahydrofuran; dichloromethane; 1.2: Horner-Wadsworth-Emmons reaction / 2.1: Diels-Alder cycloaddition;

DOI:10.1021/ja003712y

upstream raw materials:

cyclopenta-1,3-diene

(E)-3-[(1R,3S)-3-((E)-2-Phenethyloxycarbonyl-vinyl)-cyclopentyl]-acrylic acid phenethyl ester

norborn-2-ene

2,3-dihydroxybicyclo[2.2.1]hept-5-an

Downstream raw materials:

C₃₅H₃₈O₄

C₃₅H₄₆O₈