N-[(4-Chlorophenyl)sulfonyl]-2-methylalanine

Base Information

Chemical Name:N-[(4-Chlorophenyl)sulfonyl]-2-methylalanine
CAS No.:59724-71-9
Molecular Formula:C₁₀H₁₂ClNO₄S
Molecular Weight:277.729
Hs Code.:
DSSTox Substance ID:DTXSID301258003

Synonyms:N-[(4-Chlorophenyl)sulfonyl]-2-methylalanine;Oprea1_043948;SCHEMBL14676570;DTXSID301258003;AKOS008967328;59724-71-9

Suppliers and Price of N-[(4-Chlorophenyl)sulfonyl]-2-methylalanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[(4-Chlorophenyl)sulfonyl]-2-methylalanine

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:277.0175567
Heavy Atom Count:17
Complexity:380

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)Cl

Technology Process of N-[(4-Chlorophenyl)sulfonyl]-2-methylalanine

There total 1 articles about N-[(4-Chlorophenyl)sulfonyl]-2-methylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 62-57-7
2-Aminoisobutyric acid

: 98-60-2
4-chlorobenzenesulfonyl chloride

: 59724-71-9
2-(4-chlorobenzenesulfonylamino)-2-methylpropionic acid

Guidance literature:: With sodium hydroxide;
DOI:10.1111/j.2042-7158.1962.tb11132.x

Reference yield: 87.0%

: 59724-71-9
2-(4-chlorobenzenesulfonylamino)-2-methylpropionic acid

: C₁₀H₁₀⁽²⁾H₂ClNO₄S

Guidance literature:: With tetradeuterioacetic acid; water-d2; palladium diacetate; potassium carbonate; at 120 ℃; for 18h; regioselective reaction; Sealed tube;
DOI:10.1016/j.tet.2018.06.024

Reference yield:

: 59724-71-9
2-(4-chlorobenzenesulfonylamino)-2-methylpropionic acid

: 4-chlorobenzenesulfonamide-2,6-d₂

Guidance literature:: Multi-step reaction with 2 steps

1: tetradeuterioacetic acid; palladium diacetate; potassium carbonate; water-d2 / 18 h / 120 °C / Sealed tube

2: copper(II) oxide / dimethyl sulfoxide / 12 h / 120 °C / Sealed tube

With tetradeuterioacetic acid; water-d2; palladium diacetate; potassium carbonate; copper(II) oxide; In dimethyl sulfoxide;
DOI:10.1016/j.tet.2018.06.024