N¹,N²-diphenyl-2-(N-phenylstearoylamido)isobutyramidine hydrochloride

Base Information

Chemical Name:N¹,N²-diphenyl-2-(N-phenylstearoylamido)isobutyramidine hydrochloride
CAS No.:170353-66-9
Molecular Formula:C₄₀H₅₇N₃O*ClH
Molecular Weight:632.373
Hs Code.:

N<SUP>1</SUP>,N<SUP>2</SUP>-diphenyl-2-(N-phenylstearoylamido)isobutyramidine hydrochloride

Synonyms:N¹,N²-diphenyl-2-(N-phenylstearoylamido)isobutyramidine hydrochloride

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Chemical Property of N¹,N²-diphenyl-2-(N-phenylstearoylamido)isobutyramidine hydrochloride

Chemical Property:

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Technology Process of N¹,N²-diphenyl-2-(N-phenylstearoylamido)isobutyramidine hydrochloride

There total 5 articles about N¹,N²-diphenyl-2-(N-phenylstearoylamido)isobutyramidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: N¹,N²-diphenyl-2-phenylaminoisobutyramidine

: 112-76-5
Stearoyl chloride

: 170353-66-9
N¹,N²-diphenyl-2-(N-phenylstearoylamido)isobutyramidine hydrochloride

Guidance literature:: In diethyl ether; at 5 - 20 ℃;
DOI:10.1016/j.bmcl.2013.02.053

Reference yield:

: N-phenylmethacrylimidoyl chloride

: 170353-66-9
N¹,N²-diphenyl-2-(N-phenylstearoylamido)isobutyramidine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: diethyl ether / 5 - 20 °C

2: ammonium hydroxide / dichloromethane / 3 h

3: diethyl ether / 5 - 20 °C

With ammonium hydroxide; In diethyl ether; dichloromethane;
DOI:10.1016/j.bmcl.2013.02.053

Reference yield:

: 1611-83-2
2-methyl-N-phenylacrylamide

: 170353-66-9
N¹,N²-diphenyl-2-(N-phenylstearoylamido)isobutyramidine hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: phosphorus pentachloride / benzene / 7 h / 5 - 50 °C

2: diethyl ether / 5 - 20 °C

3: ammonium hydroxide / dichloromethane / 3 h

4: diethyl ether / 5 - 20 °C

With ammonium hydroxide; phosphorus pentachloride; In diethyl ether; dichloromethane; benzene;
DOI:10.1016/j.bmcl.2013.02.053