Technology Process of (R)-2-<(3,4-Dimethoxyphenyl)methyl>-3-hydroxypropyl acetate
There total 8 articles about (R)-2-<(3,4-Dimethoxyphenyl)methyl>-3-hydroxypropyl acetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Lipase PS;
at 20 ℃;
for 3h;
enantioselective reaction;
Inert atmosphere;
Enzymatic reaction;
DOI:10.1080/14786419.2021.1922403
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 90 percent / LiAlH4 / tetrahydrofuran
2: 96 percent / Pseudomonas fluorescens lipase / diisopropyl ether; H2O
With
lithium aluminium tetrahydride; pseudomonas fluorescens lipase;
In
tetrahydrofuran; di-isopropyl ether; water;
DOI:10.1016/0960-894X(96)00158-8
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 100 percent / PBr3 / diethyl ether
2: 76 percent / NaH / tetrahydrofuran
3: 90 percent / LiAlH4 / tetrahydrofuran
4: 96 percent / Pseudomonas fluorescens lipase / diisopropyl ether; H2O
With
lithium aluminium tetrahydride; pseudomonas fluorescens lipase; phosphorus tribromide; sodium hydride;
In
tetrahydrofuran; diethyl ether; di-isopropyl ether; water;
DOI:10.1016/0960-894X(96)00158-8
