N-<(benzyloxy)carbonyl>-2-(trans-5-(ethoxycarbonyl)-4-pentenyl)-4-(triethylsilyloxy)-1,2-dihydropyridine

Base Information

Chemical Name:N-<(benzyloxy)carbonyl>-2-(trans-5-(ethoxycarbonyl)-4-pentenyl)-4-(triethylsilyloxy)-1,2-dihydropyridine
CAS No.:141584-10-3
Molecular Formula:C₂₇H₃₉NO₅Si
Molecular Weight:485.696
Hs Code.:

Synonyms:N-<(benzyloxy)carbonyl>-2-(trans-5-(ethoxycarbonyl)-4-pentenyl)-4-(triethylsilyloxy)-1,2-dihydropyridine

Suppliers and Price of N-<(benzyloxy)carbonyl>-2-(trans-5-(ethoxycarbonyl)-4-pentenyl)-4-(triethylsilyloxy)-1,2-dihydropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-<(benzyloxy)carbonyl>-2-(trans-5-(ethoxycarbonyl)-4-pentenyl)-4-(triethylsilyloxy)-1,2-dihydropyridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-<(benzyloxy)carbonyl>-2-(trans-5-(ethoxycarbonyl)-4-pentenyl)-4-(triethylsilyloxy)-1,2-dihydropyridine

There total 5 articles about N-<(benzyloxy)carbonyl>-2-(trans-5-(ethoxycarbonyl)-4-pentenyl)-4-(triethylsilyloxy)-1,2-dihydropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 994-30-9
triethylsilyl chloride

: 141584-02-3
N-<(benzyloxy)carbonyl>-2-<(E)-5-(ethoxycarbonyl)-4-pentenyl>-2,3-dihydro-4-pyridone

: 141584-10-3
N-<(benzyloxy)carbonyl>-2-(trans-5-(ethoxycarbonyl)-4-pentenyl)-4-(triethylsilyloxy)-1,2-dihydropyridine

Guidance literature:: With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 1h;
DOI:10.1021/jo00041a011

Reference yield:

: 620-08-6,1232006-56-2
4-methoxypyridine

: 141584-10-3
N-<(benzyloxy)carbonyl>-2-(trans-5-(ethoxycarbonyl)-4-pentenyl)-4-(triethylsilyloxy)-1,2-dihydropyridine

Guidance literature:: Multi-step reaction with 4 steps

2: 1) (COCl)2, DMSO, 2) Et₃N / 1) CH₂Cl₂, -50 to -60 deg C, 15 min, 2) CH₂Cl₂, 10 min

3: KOtBu / 1) THF, 0 deg C, 10 min, 2) THF, a) -78 deg C, 15 min, b) r.t., 7 h

4: 100 percent / sodium bis(trimethylsilyl)amide / tetrahydrofuran / 1 h / -78 °C

With oxalyl dichloride; potassium tert-butylate; sodium hexamethyldisilazane; dimethyl sulfoxide; triethylamine; In tetrahydrofuran;
DOI:10.1021/jo00041a011

Reference yield:

: 107971-44-8
N-<(benzyloxy)carbonyl>-2-(4-hydroxybutyl)-2,3-dihydro-4-pyridone

: 141584-10-3
N-<(benzyloxy)carbonyl>-2-(trans-5-(ethoxycarbonyl)-4-pentenyl)-4-(triethylsilyloxy)-1,2-dihydropyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 1) (COCl)2, DMSO, 2) Et₃N / 1) CH₂Cl₂, -50 to -60 deg C, 15 min, 2) CH₂Cl₂, 10 min

2: KOtBu / 1) THF, 0 deg C, 10 min, 2) THF, a) -78 deg C, 15 min, b) r.t., 7 h

3: 100 percent / sodium bis(trimethylsilyl)amide / tetrahydrofuran / 1 h / -78 °C

With oxalyl dichloride; potassium tert-butylate; sodium hexamethyldisilazane; dimethyl sulfoxide; triethylamine; In tetrahydrofuran;
DOI:10.1021/jo00041a011