Hexanamide, N-[(3S,4R)-tetrahydro-4-hydroxy-2-oxo-3-furanyl]- (9CI)

Base Information

Chemical Name:Hexanamide, N-[(3S,4R)-tetrahydro-4-hydroxy-2-oxo-3-furanyl]- (9CI)
CAS No.:428510-08-1
Molecular Formula:C₁₀H₁₇NO₄
Molecular Weight:215.249
Hs Code.:
Mol file:428510-08-1.mol

Synonyms:Hexanamide, N-[(3S,4R)-tetrahydro-4-hydroxy-2-oxo-3-furanyl]- (9CI)

Suppliers and Price of Hexanamide, N-[(3S,4R)-tetrahydro-4-hydroxy-2-oxo-3-furanyl]- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of Hexanamide, N-[(3S,4R)-tetrahydro-4-hydroxy-2-oxo-3-furanyl]- (9CI)

Chemical Property:

PSA：75.63000
LogP:0.36010

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Hexanamide, N-[(3S,4R)-tetrahydro-4-hydroxy-2-oxo-3-furanyl]- (9CI)

There total 4 articles about Hexanamide, N-[(3S,4R)-tetrahydro-4-hydroxy-2-oxo-3-furanyl]- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 22102-92-7
hexanoic acid hydroxysuccinimide ester

: 92754-75-1
(2S,3R)-2-<(benzyloxycarbonyl)amino>-3-hydroxy-4-butanolide

: 428510-08-1
Hexanoic acid ((3S,4R)-4-hydroxy-2-oxo-tetrahydro-furan-3-yl)-amide

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; under 760 Torr;
DOI:10.1016/S0960-894X(01)00756-9

Reference yield:

: 56762-93-7
methyl (S)-2-(benzyloxycarbonylamino)-4-methylmercaptobutanoate

: 428510-08-1
Hexanoic acid ((3S,4R)-4-hydroxy-2-oxo-tetrahydro-furan-3-yl)-amide

Guidance literature:: Multi-step reaction with 4 steps

1.1: aq. NaIO₄ / methanol

2.1: 71 percent / xylene / Heating

3.1: aq. K₂OsO₄; NMO; AcOH / acetone

3.2: 43 percent / PTSA / toluene / 100 °C

4.1: 74 percent / H₂ / 5 percent Pd/C / methanol / 760 Torr

With potassium osmate(VI); sodium periodate; N-methyl-2-indolinone; hydrogen; acetic acid; palladium on activated charcoal; In methanol; acetone; xylene;
DOI:10.1016/S0960-894X(01)00756-9

Reference yield:

: 75266-40-9
N-benzyloxycarbonyl-L-α-vinylglycine methyl ester

: 428510-08-1
Hexanoic acid ((3S,4R)-4-hydroxy-2-oxo-tetrahydro-furan-3-yl)-amide

Guidance literature:: Multi-step reaction with 2 steps

1.1: aq. K₂OsO₄; NMO; AcOH / acetone

1.2: 43 percent / PTSA / toluene / 100 °C

2.1: 74 percent / H₂ / 5 percent Pd/C / methanol / 760 Torr

With potassium osmate(VI); N-methyl-2-indolinone; hydrogen; acetic acid; palladium on activated charcoal; In methanol; acetone;
DOI:10.1016/S0960-894X(01)00756-9