92754-75-1Relevant articles and documents
Synthesis of new 3- and 4-substituted analogues of acyl homoserine lactone quorum sensing autoinducers
Olsen,Severinsen,Rasmussen,Hentzer,Givskov,Nielsen
, p. 325 - 328 (2007/10/03)
The quorum sensing mechanism in Gram-negative bacteria uses small intercellular signal molecules, N-acyl-homoserine lactones (AHLs), to control transcription of specific genes in relation to population density. In this communication, we describe the parallel synthesis of new AHL analogues, in which substituents have been introduced into the 3- and 4-positions of the lactone ring. These analogues have been screened for their ability to activate and inhibit a Vibrio fischeri LuxI/LuxR-derived quorum sensing reporter system.
Synthesis of carumonam (AMA-1080) and a related compound starting from (2R,3R)-epoxysuccinic acid
Sendai,Hashiguchi,Tomimoto,et al.
, p. 3798 - 3810 (2007/10/02)
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