3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol hydrobromide

Base Information

• Chemical Name: 3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol hydrobromide
• CAS No.: 1356475-57-4
• Molecular Formula: BrH*C₁₄H₂₃NO
• Molecular Weight: 302.255

Synonyms:3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol hydrobromide

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Chemical Property of 3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol hydrobromide

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol hydrobromide

There total 2 articles about 3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

tapentadol (175591-23-8) → 3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol hydrobromide (1356475-57-4)

Guidance literature:

With hydrogen bromide; In ethyl acetate; for 3h;

Reference yield: 95.0%

tapentadol (175591-23-8) + hydrogen bromide (10035-10-6,12258-64-9) → 3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol hydrobromide (1356475-57-4)

Guidance literature:

In water; ethyl acetate; for 3h;

Reference yield:

3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol hydrobromide (1356475-57-4) + maleic acid (110-16-7,26099-09-2) → tapentadol maleate

Guidance literature:

3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol hydrobromide; With sodium hydroxide; In tert-butyl methyl ether; water;

maleic acid; In tert-butyl methyl ether; isopropyl alcohol; at 50 ℃;

upstream raw materials:

tapentadol

hydrogen bromide

Downstream raw materials:

tapentadol