(4R,5S,4'S,5'R)-4,5-dihydro-2-phenyl-4-[(1',5'-dimethyl-4'-phenylimidazolidin-2'-on-3'-yl)carbonyl]-5-isopropyloxazole

Base Information

Chemical Name:(4R,5S,4'S,5'R)-4,5-dihydro-2-phenyl-4-[(1',5'-dimethyl-4'-phenylimidazolidin-2'-on-3'-yl)carbonyl]-5-isopropyloxazole
CAS No.:347885-26-1
Molecular Formula:C₂₄H₂₇N₃O₃
Molecular Weight:405.497
Hs Code.:

Synonyms:(4R,5S,4'S,5'R)-4,5-dihydro-2-phenyl-4-[(1',5'-dimethyl-4'-phenylimidazolidin-2'-on-3'-yl)carbonyl]-5-isopropyloxazole

Suppliers and Price of (4R,5S,4'S,5'R)-4,5-dihydro-2-phenyl-4-[(1',5'-dimethyl-4'-phenylimidazolidin-2'-on-3'-yl)carbonyl]-5-isopropyloxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4R,5S,4'S,5'R)-4,5-dihydro-2-phenyl-4-[(1',5'-dimethyl-4'-phenylimidazolidin-2'-on-3'-yl)carbonyl]-5-isopropyloxazole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4R,5S,4'S,5'R)-4,5-dihydro-2-phenyl-4-[(1',5'-dimethyl-4'-phenylimidazolidin-2'-on-3'-yl)carbonyl]-5-isopropyloxazole

There total 4 articles about (4R,5S,4'S,5'R)-4,5-dihydro-2-phenyl-4-[(1',5'-dimethyl-4'-phenylimidazolidin-2'-on-3'-yl)carbonyl]-5-isopropyloxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 347885-22-7
(4S,5R,2'R,3'S)-1,5-dimethyl-4-phenyl-3-[(2'-N-benzoyl-aziridinyl-3'-isopropyl)carbonyl]-imidazolidin-2-one

: 347885-26-1
(4R,5S,4'S,5'R)-4,5-dihydro-2-phenyl-4-[(1',5'-dimethyl-4'-phenylimidazolidin-2'-on-3'-yl)carbonyl]-5-isopropyloxazole

Guidance literature:: With boron trifluoride diethyl etherate; In dichloromethane; at 20 ℃; for 1h;
DOI:10.1016/S0957-4166(01)00084-2

Reference yield:

: 98-88-4
benzoyl chloride

: 347885-26-1
(4R,5S,4'S,5'R)-4,5-dihydro-2-phenyl-4-[(1',5'-dimethyl-4'-phenylimidazolidin-2'-on-3'-yl)carbonyl]-5-isopropyloxazole

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / Et₃N / CH₂Cl₂ / 2 h / 20 °C

2: 95 percent / BF₃*OEt₂ / CH₂Cl₂ / 1 h / 20 °C

With boron trifluoride diethyl etherate; triethylamine; In dichloromethane;
DOI:10.1016/S0957-4166(01)00084-2

Reference yield:

: 347885-18-1
(4S,5R,2'R,3'S)-1,5-dimethyl-4-phenyl-3-[(2'-aziridinyl-3'-isopropyl)carbonyl]-imidazolidin-2-one

: 347885-26-1
(4R,5S,4'S,5'R)-4,5-dihydro-2-phenyl-4-[(1',5'-dimethyl-4'-phenylimidazolidin-2'-on-3'-yl)carbonyl]-5-isopropyloxazole

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / Et₃N / CH₂Cl₂ / 2 h / 20 °C

2: 95 percent / BF₃*OEt₂ / CH₂Cl₂ / 1 h / 20 °C

With boron trifluoride diethyl etherate; triethylamine; In dichloromethane;
DOI:10.1016/S0957-4166(01)00084-2