(3Z)-4,5,6,7-tetrahydro-3-benzylideneisobenzofuran-1(3H)-one

Base Information

• Chemical Name: (3Z)-4,5,6,7-tetrahydro-3-benzylideneisobenzofuran-1(3H)-one
• CAS No.: 122135-92-6
• Molecular Formula: C₁₅H₁₄O₂
• Molecular Weight: 226.275
• Mol file: 122135-92-6.mol

Synonyms:(3Z)-4,5,6,7-tetrahydro-3-benzylideneisobenzofuran-1(3H)-one

Chemical Property of (3Z)-4,5,6,7-tetrahydro-3-benzylideneisobenzofuran-1(3H)-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3Z)-4,5,6,7-tetrahydro-3-benzylideneisobenzofuran-1(3H)-one

There total 12 articles about (3Z)-4,5,6,7-tetrahydro-3-benzylideneisobenzofuran-1(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2-bromocyclohex-1-enecarboxylic acid (68965-62-8) + phenylacetylene (536-74-3) → (3Z)-4,5,6,7-tetrahydro-3-benzylideneisobenzofuran-1(3H)-one (122135-92-6)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 0.5h; Reagent/catalyst; Solvent; Temperature; Microwave irradiation;

DOI:10.1016/j.jorganchem.2015.05.040

Reference yield: 52.0%

carbon dioxide (124-38-9,18923-20-1) + trimethyl(2-(phenylethynyl)cyclohex-2-en-1-yl)silane → (3Z)-4,5,6,7-tetrahydro-3-benzylideneisobenzofuran-1(3H)-one (122135-92-6) + C15H14O2

Guidance literature:

With ethanol; [1,3-bis(2,6-diisopropyl-phenyl)imidazol-2-ylidene] silver(I) chloro; cesium fluoride; In N,N-dimethyl-formamide; at 60 ℃; for 24h; under 7500.75 Torr; Autoclave;

DOI:10.1021/acs.orglett.5b03023

Reference yield: 2.0%

2-bromocyclohex-1-enecarboxylic acid (68965-62-8) + phenylacetylene (536-74-3) + aniline (62-53-3) → (3Z)-4,5,6,7-tetrahydro-3-benzylideneisobenzofuran-1(3H)-one (122135-92-6) + (3Z)-3-benzylidene-2,3,4,5,6,7-hexahydro-2-phenylisoindol-1-one

Guidance literature:

With copper(l) iodide; palladium 10% on activated carbon; triphenylphosphine; In 1,4-dioxane; at 110 ℃; for 40h;

DOI:10.1002/aoc.2990

upstream raw materials:

2-bromocyclohex-1-enecarboxylic acid

phenylacetylene

2-bromocyclohex-1-ene-1-carbaldehyde

cyclohexanone