1-benzyl 4-methyl 4-{[4-(5-bromopyridin-2-yl)piperidin-1-yl]sulfonyl}piperidine-1,4-dicarboxylate

Base Information

Chemical Name:1-benzyl 4-methyl 4-{[4-(5-bromopyridin-2-yl)piperidin-1-yl]sulfonyl}piperidine-1,4-dicarboxylate
CAS No.:622387-29-5
Molecular Formula:C₂₅H₃₀BrN₃O₆S
Molecular Weight:580.5
Hs Code.:

Synonyms:1-benzyl 4-methyl 4-{[4-(5-bromopyridin-2-yl)piperidin-1-yl]sulfonyl}piperidine-1,4-dicarboxylate

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Chemical Property of 1-benzyl 4-methyl 4-{[4-(5-bromopyridin-2-yl)piperidin-1-yl]sulfonyl}piperidine-1,4-dicarboxylate

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Technology Process of 1-benzyl 4-methyl 4-{[4-(5-bromopyridin-2-yl)piperidin-1-yl]sulfonyl}piperidine-1,4-dicarboxylate

There total 1 articles about 1-benzyl 4-methyl 4-{[4-(5-bromopyridin-2-yl)piperidin-1-yl]sulfonyl}piperidine-1,4-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 622387-28-4
benzyl 4-{[4-(5-bromopyridin-2-yl)piperidin-1-yl]sulfonyl}piperidine-1-carboxylate

: 616-38-6
carbonic acid dimethyl ester

: 622387-29-5
1-benzyl 4-methyl 4-{[4-(5-bromopyridin-2-yl)piperidin-1-yl]sulfonyl}piperidine-1,4-dicarboxylate

Guidance literature:: benzyl 4-{[4-(5-bromopyridin-2-yl)piperidin-1-yl]sulfonyl}piperidine-1-carboxylate; With lithium hexamethyldisilazane; In tetrahydrofuran; at 20 ℃; for 1h;

carbonic acid dimethyl ester; In tetrahydrofuran; at 20 ℃; for 2h;

Reference yield: 100.0%

: 374063-92-0
2-hydroxy-5-bromopyrazine

: 622387-29-5
1-benzyl 4-methyl 4-{[4-(5-bromopyridin-2-yl)piperidin-1-yl]sulfonyl}piperidine-1,4-dicarboxylate

: 622387-30-8
1-benzyl 4-methyl 4-{[4-(5-butylpyridin-2-yl)piperidin-1-yl]sulfonyl}piperidine-1,4-dicarboxylate

Guidance literature:: With potassium phosphate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In tetrahydrofuran; dichloromethane; at 60 ℃; for 20h;