N-tosylcyclopentanecarboxamidine

Base Information

• Chemical Name: N-tosylcyclopentanecarboxamidine
• CAS No.: 129958-21-0
• Molecular Formula: C₁₃H₁₈N₂O₂S
• Molecular Weight: 266.364
• Mol file: 129958-21-0.mol

Synonyms:N-tosylcyclopentanecarboxamidine

Chemical Property of N-tosylcyclopentanecarboxamidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-tosylcyclopentanecarboxamidine

There total 3 articles about N-tosylcyclopentanecarboxamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

N-[1-Cyclopentyl-1-methoxy-meth-(Z)-ylidene]-4-methyl-benzenesulfonamide (121239-22-3) → N-tosylcyclopentanecarboxamidine (129958-21-0)

Guidance literature:

With ammonium hydroxide; In ethanol; at 0 ℃; for 5h;

Reference yield:

4-toluenesulfonyl azide (941-55-9) + C14H19NO2S → N-tosylcyclopentanecarboxamidine (129958-21-0)

Guidance literature:

With air; In dimethyl sulfoxide; at 70 ℃; Sealed tube;

DOI:10.1021/jacs.8b11039

Reference yield:

cyclopentylacetylene (930-51-8) → N-tosylcyclopentanecarboxamidine (129958-21-0)

Guidance literature:

Multi-step reaction with 2 steps

1: trimethylsilylazide; silver orthophosphate; water / dimethyl sulfoxide / 4 h / 70 °C / Sealed tube

2: air / dimethyl sulfoxide / 70 °C / Sealed tube

With silver orthophosphate; trimethylsilylazide; water; In dimethyl sulfoxide;

DOI:10.1021/jacs.8b11039

upstream raw materials:

N-[1-Cyclopentyl-1-methoxy-meth-(Z)-ylidene]-4-methyl-benzenesulfonamide

4-toluenesulfonyl azide

cyclopentylacetylene