[2-(tert-Butyl-dimethyl-silanyl)-eth-(E)-ylidene]-cyclohexyl-amine

Base Information

• Chemical Name: [2-(tert-Butyl-dimethyl-silanyl)-eth-(E)-ylidene]-cyclohexyl-amine
• CAS No.: 79705-09-2
• Molecular Formula: C₁₄H₂₉NSi
• Molecular Weight: 239.476
• Mol file: 79705-09-2.mol

Synonyms:[2-(tert-Butyl-dimethyl-silanyl)-eth-(E)-ylidene]-cyclohexyl-amine

Chemical Property of [2-(tert-Butyl-dimethyl-silanyl)-eth-(E)-ylidene]-cyclohexyl-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [2-(tert-Butyl-dimethyl-silanyl)-eth-(E)-ylidene]-cyclohexyl-amine

There total 1 articles about [2-(tert-Butyl-dimethyl-silanyl)-eth-(E)-ylidene]-cyclohexyl-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-ethylidenecyclohexylamine (113832-57-8,1193-93-7) + tert-butyldimethylsilyl chloride (18162-48-6) → [2-(tert-Butyl-dimethyl-silanyl)-eth-(E)-ylidene]-cyclohexyl-amine (79705-09-2)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; 1.) O deg C, 15 min, 2.) -78 deg C to room temperature;

DOI:10.1021/ja00410a060

Reference yield:

[2-(tert-Butyl-dimethyl-silanyl)-eth-(E)-ylidene]-cyclohexyl-amine (79705-09-2) → 2-[2-(tert-Butyl-dimethyl-silanyl)-1-hydroxy-ethyl]-cyclohexanone (79705-17-2)

Guidance literature:

Multi-step reaction with 2 steps

1: AcOH, H₂O / CH₂Cl₂ / 0.08 h / Ambient temperature

2: LDA / tetrahydrofuran / 1.5 h / -78 °C

With water; acetic acid; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane;

DOI:10.1021/ja00410a060

Reference yield:

[2-(tert-Butyl-dimethyl-silanyl)-eth-(E)-ylidene]-cyclohexyl-amine (79705-09-2) → 2-[2-(tert-Butyl-dimethyl-silanyl)-1-hydroxy-ethyl]-1-vinyl-cyclohexanol (79705-24-1)

Guidance literature:

Multi-step reaction with 3 steps

1: AcOH, H₂O / CH₂Cl₂ / 0.08 h / Ambient temperature

2: LDA / tetrahydrofuran / 1.5 h / -78 °C

3: tetrahydrofuran / 4 h / Ambient temperature

With water; acetic acid; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane;

DOI:10.1021/ja00410a060

upstream raw materials:

N-ethylidenecyclohexylamine

tert-butyldimethylsilyl chloride

Downstream raw materials:

[2-(tert-Butyl-dimethyl-silanyl)-oct-(E)-ylidene]-cyclohexyl-amine

2-[2-(tert-Butyl-dimethyl-silanyl)-1-hydroxy-ethyl]-cyclohexanone

2-[2-(tert-Butyl-dimethyl-silanyl)-1-hydroxy-ethyl]-1-vinyl-cyclohexanol