rac-6β-((Ξ)-2-benzyloxycarbonyl-2-thiophen-3-yl-acetylamino)-6α-methoxy-penicillanic acid benzyl ester

Base Information

• Chemical Name: rac-6β-((Ξ)-2-benzyloxycarbonyl-2-thiophen-3-yl-acetylamino)-6α-methoxy-penicillanic acid benzyl ester
• CAS No.: 61545-07-1
• Molecular Formula: C₃₀H₃₀N₂O₇S₂
• Molecular Weight: 594.709
• Mol file: 61545-07-1.mol

Synonyms:rac-6β-((Ξ)-2-benzyloxycarbonyl-2-thiophen-3-yl-acetylamino)-6α-methoxy-penicillanic acid benzyl ester

Chemical Property of rac-6β-((Ξ)-2-benzyloxycarbonyl-2-thiophen-3-yl-acetylamino)-6α-methoxy-penicillanic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of rac-6β-((Ξ)-2-benzyloxycarbonyl-2-thiophen-3-yl-acetylamino)-6α-methoxy-penicillanic acid benzyl ester

There total 2 articles about rac-6β-((Ξ)-2-benzyloxycarbonyl-2-thiophen-3-yl-acetylamino)-6α-methoxy-penicillanic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6β-amino-6α-methoxy-penicillanic acid benzyl ester (35353-32-3) + monobenzyl 3-thienylmalonic acid chloride (50893-38-4) → rac-6β-((Ξ)-2-benzyloxycarbonyl-2-thiophen-3-yl-acetylamino)-6α-methoxy-penicillanic acid benzyl ester (61545-07-1)

Guidance literature:

With pyridine; In dichloromethane;

Reference yield:

→ (S)-6-(2-Benzyloxycarbonyl-2-thiophen-3-yl-acetylamino)-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester (61545-07-1)

Guidance literature:

entspr. Aminopenicillanester, entspr. Malonylchlorid;

Reference yield:

rac-6β-((Ξ)-2-benzyloxycarbonyl-2-thiophen-3-yl-acetylamino)-6α-methoxy-penicillanic acid benzyl ester (61545-07-1) → rac-6β-((Ξ)-2-carboxy-2-thiophen-3-yl-acetylamino)-6α-methoxy-penicillanic acid (66148-78-5,94493-48-8,94536-98-8)

Guidance literature:

With hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In methanol; water;

upstream raw materials:

6β-amino-6α-methoxy-penicillanic acid benzyl ester

monobenzyl 3-thienylmalonic acid chloride

Downstream raw materials:

rac-6β-((Ξ)-2-carboxy-2-thiophen-3-yl-acetylamino)-6α-methoxy-penicillanic acid