trans-(+/-)-2-(3-cyanopropyl)-8-fluoro-5-(4-fluorophenyl)-2,3,4,4a,5,9b-hexahydro-1H-pyrido<4,3-b>indole

Base Information

Chemical Name:trans-(+/-)-2-(3-cyanopropyl)-8-fluoro-5-(4-fluorophenyl)-2,3,4,4a,5,9b-hexahydro-1H-pyrido<4,3-b>indole
CAS No.:77378-64-4
Molecular Formula:C₂₁H₂₁F₂N₃
Molecular Weight:353.415
Hs Code.:

Synonyms:trans-(+/-)-2-(3-cyanopropyl)-8-fluoro-5-(4-fluorophenyl)-2,3,4,4a,5,9b-hexahydro-1H-pyrido<4,3-b>indole

Suppliers and Price of trans-(+/-)-2-(3-cyanopropyl)-8-fluoro-5-(4-fluorophenyl)-2,3,4,4a,5,9b-hexahydro-1H-pyrido<4,3-b>indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of trans-(+/-)-2-(3-cyanopropyl)-8-fluoro-5-(4-fluorophenyl)-2,3,4,4a,5,9b-hexahydro-1H-pyrido<4,3-b>indole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of trans-(+/-)-2-(3-cyanopropyl)-8-fluoro-5-(4-fluorophenyl)-2,3,4,4a,5,9b-hexahydro-1H-pyrido<4,3-b>indole

There total 2 articles about trans-(+/-)-2-(3-cyanopropyl)-8-fluoro-5-(4-fluorophenyl)-2,3,4,4a,5,9b-hexahydro-1H-pyrido<4,3-b>indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 628-20-6
4-Chlorobutyronitrile

: 69623-07-0
(+/-)-4a,9b-trans-8-fluoro-5-(4-fluorophenyl)-2,3,4,4a,5,9a-hexahydro-1H-pyrido<4,3-b>indole

: 77378-64-4
trans-(+/-)-2-(3-cyanopropyl)-8-fluoro-5-(4-fluorophenyl)-2,3,4,4a,5,9b-hexahydro-1H-pyrido<4,3-b>indole

Guidance literature:: With sodium carbonate; potassium iodide; In various solvent(s); 1.) from 80 deg C to 90 deg C, 18 h, 2.) from 120 deg C to 130 deg C, 72 h;
DOI:10.1021/jm00151a002