628-20-6Relevant articles and documents
Photoinduced Remote Functionalisations by Iminyl Radical Promoted C?C and C?H Bond Cleavage Cascades
Dauncey, Elizabeth M.,Morcillo, Sara P.,Douglas, James J.,Sheikh, Nadeem S.,Leonori, Daniele
supporting information, p. 744 - 748 (2017/12/13)
A photoinduced cascade strategy leading to a variety of differentially functionalised nitriles and ketones has been developed. These reactions rely on the oxidative generation of iminyl radicals from simple oximes. Radical transposition by C(sp3)?(sp3) and C(sp3)?H bond cleavage gives access to distal carbon radicals that undergo SH2 functionalisations. These mild, visible-light-mediated procedures can be used for remote fluorination, chlorination, and azidation, and were applied to the modification of bioactive and structurally complex molecules.
Efficient One-Step Transformation of Carboxylic Acids to Nitriles with the Carbon Chain Shortened by One Carbon Atom
Smushkevich, Y. I.,Smushkevich, V. Y.,Usorov, M. I.
, p. 1727 - 1736 (2007/10/03)
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FUNCTIONAL GROUP-TOLERANT HYDROALKYLATION OF ELECTRON-DEFICIENT OLEFINS THROUGH COPPER(I)-CATALYZED PHOTOADDITION OF ORGANIC HALIDES FOLLOWED BY REDUCTION WITH ZINC
Mitani, Michiharu,Hirayama, Hiroyuki
, p. 1562 - 1572 (2007/10/02)
A method of accomplishing hydroalkylation of electron-deficient olefins which tolerates a variety of functional groups, in which organic halides and electron-deficient olefins are subjected to a photoreaction catalyzed by the CuBr-Bun3P complex followed by treatment with Zn dust in the presence of AcOH, has been developed.