AC-ASP-OME

Base Information

• Chemical Name: AC-ASP-OME
• CAS No.: 4910-47-8
• Molecular Formula: C7H11 N O5
• Molecular Weight: 189.168
• Mol file: 4910-47-8.mol

Synonyms:Asparticacid, N-acetyl-, 1-methyl ester (7CI); Aspartic acid, N-acetyl-, 1-methylester, L- (8CI); N-Acetyl-L-Aspartic acid 1-methyl ester

Chemical Property of AC-ASP-OME

Chemical Property:

• PSA: 92.70000
• LogP: -0.47030
• Storage Temp.: Store at 0-5°C

Purity/Quality:

99% ^*data from raw suppliers

Acetyl-L-asparticacidα-methylester,98%(NMR) 98%(NMR) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of AC-ASP-OME

There total 3 articles about AC-ASP-OME which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

N-α-acetyl-L-aspartic acid α,β-dimethylester (57289-64-2) → N-Acetyl-asparaginsaeure-α-methylester (4910-47-8)

Guidance literature:

With water; sodium hydroxide; In aq. phosphate buffer; at 20 ℃; for 47h; pH=6; Enzymatic reaction;

Reference yield: 70.0%

(S)-N-acetylphenylalanine (3618-96-0) → N-Acetyl-asparaginsaeure-α-methylester (4910-47-8)

Guidance literature:

With ruthenium trichloride; sodium periodate; In tetrachloromethane; acetonitrile; for 60h;

Reference yield:

→ 2-Acetylamino-succinic acid 1-methyl ester (4910-47-8)

Guidance literature:

L-Asparaginsaeure-α-methylester mit Ac2O;

upstream raw materials:

(S)-N-acetylphenylalanine

N-α-acetyl-L-aspartic acid α,β-dimethylester

Downstream raw materials:

N-[(3S)-1-[4-[(3-fluorophenyl)methoxy]phenyl]-5-oxo-pyrrolidin-3-yl]acetamide

Refernces

• 1、 Ranganathan,Muraleedharan,Bhattacharyya,Kundu. "The Preference Profile in Ruthenium Tetroxide Oxidations". . p. 583 - 589. Retrieved 2007/10/03.