(R)-3-hydroxy-5-methylhexanoic acid

Base Information

Chemical Name:(R)-3-hydroxy-5-methylhexanoic acid
CAS No.:132328-50-8
Molecular Formula:C₇H₁₄O₃
Molecular Weight:146.186
Hs Code.:
European Community (EC) Number:888-473-7
Nikkaji Number:J1.084.443F

Synonyms:(R)-3-hydroxy-5-methylhexanoic acid;132328-50-8;SCHEMBL4748781;SCAWECGFPWPHAR-ZCFIWIBFSA-N;AKOS006375466;(3R)-3-hydroxy-5-methylhexanoic acid;(3r)-3-hydroxy-5-methyl-hexanoic acid;EN300-1837967

Suppliers and Price of (R)-3-hydroxy-5-methylhexanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of (R)-3-hydroxy-5-methylhexanoic acid

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:146.094294304
Heavy Atom Count:10
Complexity:109

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)CC(CC(=O)O)O
Isomeric SMILES:CC(C)C[C@H](CC(=O)O)O

Technology Process of (R)-3-hydroxy-5-methylhexanoic acid

There total 1 articles about (R)-3-hydroxy-5-methylhexanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 30414-55-2
methyl 5-methyl-3-oxohexanoate

: 132328-50-8
(R)-(-)-3-hydroxy-5-methyl-hexanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / H₂ / [Ru((R)-binap)Cl₂] / methanol / 72 h / 20 °C / 76000 Torr

2: 74 percent / KOH / ethanol / 24 h / 0 - 20 °C

With potassium hydroxide; hydrogen; RuCl₂[S-BINAP]; In methanol; ethanol;
DOI:10.1002/1522-2675(200202)85:2<633::AID-HLCA633>3.0.CO;2-1

Reference yield: 93.0%

: 100-39-0
benzyl bromide

: 132328-50-8
(R)-(-)-3-hydroxy-5-methyl-hexanoic acid

: 223617-41-2
benzyl (R)-3-hydroxy-5-methylhexanoate

Guidance literature:: With sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 20 ℃; for 24h;
DOI:10.1002/1522-2675(200202)85:2<633::AID-HLCA633>3.0.CO;2-1

Reference yield: 77.0%

: 42001-91-2
(2S,3R)-benzyl 2-amino-3-(benzyloxy)butanoate oxalate

: 132328-50-8
(R)-(-)-3-hydroxy-5-methyl-hexanoic acid

: C₂₅H₃₃NO₅

Guidance literature:: (R)-(-)-3-hydroxy-5-methyl-hexanoic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 0 ℃; for 0.0833333h;

(2S,3R)-benzyl 2-amino-3-(benzyloxy)butanoate oxalate; With 2,4,6-trimethyl-pyridine; In N,N-dimethyl-formamide; at 40 ℃; for 2h;
DOI:10.1002/anie.201410270