10-Benzyloxymethyl-3,6,9,12,15,18-hexaoxa-1,20-eicosandiol bis-tetrahydropyranyl ether

Base Information

• Chemical Name: 10-Benzyloxymethyl-3,6,9,12,15,18-hexaoxa-1,20-eicosandiol bis-tetrahydropyranyl ether
• CAS No.: 99557-31-0
• Molecular Formula: C₃₂H₅₄O₁₁
• Molecular Weight: 614.774
• Mol file: 99557-31-0.mol

Synonyms:10-Benzyloxymethyl-3,6,9,12,15,18-hexaoxa-1,20-eicosandiol bis-tetrahydropyranyl ether

Chemical Property of 10-Benzyloxymethyl-3,6,9,12,15,18-hexaoxa-1,20-eicosandiol bis-tetrahydropyranyl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 10-Benzyloxymethyl-3,6,9,12,15,18-hexaoxa-1,20-eicosandiol bis-tetrahydropyranyl ether

There total 1 articles about 10-Benzyloxymethyl-3,6,9,12,15,18-hexaoxa-1,20-eicosandiol bis-tetrahydropyranyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-benzyloxypropan-1,2-diol (13071-59-5,17325-85-8,56552-80-8,4799-67-1) + 2-(2'-(2''-Chloroethoxy)ethoxy)ethyl-2-tetrahydro-2H-pyran (85539-28-2) → 10-Benzyloxymethyl-3,6,9,12,15,18-hexaoxa-1,20-eicosandiol bis-tetrahydropyranyl ether (99557-31-0)

Guidance literature:

With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; at 65 ℃; for 72h;

DOI:10.1021/jo00265a026

Reference yield: 100.0%

10-Benzyloxymethyl-3,6,9,12,15,18-hexaoxa-1,20-eicosandiol bis-tetrahydropyranyl ether (99557-31-0) → 3,6,9,12,15,18-hexaoxa-10-(benzyloxymethyl)-1,20-eicosanediol (99557-30-9)

Guidance literature:

With hydrogenchloride; In methanol; dichloromethane; for 2h; Ambient temperature;

DOI:10.1055/s-1985-31195

Reference yield:

10-Benzyloxymethyl-3,6,9,12,15,18-hexaoxa-1,20-eicosandiol bis-tetrahydropyranyl ether (99557-31-0) → benzyloxymethyl-30-crown-10 (91472-20-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / conc. aq. HCl / CH₂Cl₂; methanol / 2 h / Ambient temperature

2: 39 percent / t-C₄H₉-OK / tetrahydrofuran / 216 h / Ambient temperature

With hydrogenchloride; potassium tert-butylate; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1055/s-1985-31195

upstream raw materials:

3-benzyloxypropan-1,2-diol

2-(2'-(2''-Chloroethoxy)ethoxy)ethyl-2-tetrahydro-2H-pyran

Downstream raw materials:

3,6,9,12,15,18-hexaoxa-10-(benzyloxymethyl)-1,20-eicosanediol

benzyloxymethyl-30-crown-10

benzyloxymethyl-21-crown-7