1-O-BENZYL-RAC-GLYCEROL

Base Information

• Chemical Name: 1-O-BENZYL-RAC-GLYCEROL
• CAS No.: 13071-59-5
• Molecular Formula: C₁₀H₁₄O₃
• Molecular Weight: 182.219
• Mol file: 13071-59-5.mol

Synonyms:(+/-)-BENZYL GLYCEROL;DL-ALPHA-O-BENZYLGLYCEROL;3-PHENYLMETHOXY-1,2-PROPANEDIOL;dl-A-O-benzylglycerol;dl-α-o-benzylglycerol;

Chemical Property of 1-O-BENZYL-RAC-GLYCEROL

Chemical Property:

• Refractive Index: n20/D 1.533
• PSA: 49.69000
• Density: 1.140 g/mL at 20 °C(lit.)
• LogP: 0.55640
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-O-BENZYL-RAC-GLYCEROL

There total 82 articles about 1-O-BENZYL-RAC-GLYCEROL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Benzyloxymethyl-oxiran (2930-05-4) + water-tetrahydrofuran → 3-benzyloxypropan-1,2-diol (13071-59-5,17325-85-8,56552-80-8,4799-67-1)

Guidance literature:

With sulfuric acid;

Reference yield: 99.0%

4-(benzyloxymethyl)-2,2-dimethyl-1,3-dioxolane (15028-56-5) → 3-benzyloxypropan-1,2-diol (13071-59-5,17325-85-8,56552-80-8,4799-67-1)

Guidance literature:

With hydrogenchloride; In methanol; at 20 ℃; for 2h;

DOI:10.1002/chem.202003991

Reference yield: 99.0%

4-phenylmethoxymethyl-1,3-dioxolan-2-one (949-97-3) → methanol (67-56-1) + 3-benzyloxypropan-1,2-diol (13071-59-5,17325-85-8,56552-80-8,4799-67-1)

Guidance literature:

With C₂₃H₂₁MnN₂O₃P⁽¹⁺⁾*Br^(1-); potassium tert-butylate; hydrogen; In 1,4-dioxane; at 140 ℃; for 16h; under 37503.8 Torr; Autoclave;

DOI:10.1002/anie.201805630

upstream raw materials:

oxiranyl-methanol

benzyl alcohol

4-(benzyloxymethyl)-2,2-dimethyl-1,3-dioxolane

benzyl chloride

Downstream raw materials:

benzyloxyacetoaldehyde

2-Dicyanomethylene-4-benzyloxymethyl-1,3-dioxolane

<(Benzyloxy)methyl>-12-crown-4

dibenzyl glycerol

Refernces

• 1、 Boeckel, C. A. A. van,Westerduin, P.,Boom, J. H. van. "SYNTHESIS OF 2,3-DI-O-PHYTANYL-1-O-6)-MANNOSYL-α(1->2)-GLUCOSYL-α(1->1)>-SN-GLYCEROL. PURPLE MEMBRANE GLYCOLIPIDS". . p. 2819 - 2822. Retrieved 1981.
• 2、 Bhattacharya, Santanu,Ghosh, Sangita,Easwaran, Kalpathy R. K.. "Synthesis of macrocyclic diacyl/dialkyl glycerols containing disulfide tether and studies of their effects upon incorporation in DPPC membranes. Implications in the design of phospholipase A2 modulators". . p. 9232 - 9242. Retrieved 1998.
• 3、 Bhattacharya, Santanu,De, Soma,George, Shaji K.. "Synthesis and vesicle formation from novel pseudoglyceryl dimeric lipids. Evidence of formation of widely different membrane organizations with exceptional thermotropic properties". . p. 2287 - 2288. Retrieved 1997.
• 4、 Chiosso, María E.,Casella, Mónica L.,Merlo, Andrea B.. "Synthesis and catalytic evaluation of acidic carbons in the etherification of glycerol obtained from biodiesel production". . p. 107 - 114. Retrieved 2020/10/29.
• 5、 -. "POLY(PHOSPHOESTERS) FOR DELIVERY OF NUCLEIC ACIDS". Paragraph 0387. . Retrieved 2020/09/15.