[(S)-5-amino-1-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}piperazine-1-carbonyl)-pentyl]-trimethyl-ammonium

Base Information

Chemical Name:[(S)-5-amino-1-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}piperazine-1-carbonyl)-pentyl]-trimethyl-ammonium
CAS No.:928851-10-9
Molecular Formula:C₃₇H₅₁Cl₂N₆O₅S
Molecular Weight:762.821
Hs Code.:

[(S)-5-amino-1-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}piperazine-1-carbonyl)-pentyl]-trimethyl-ammonium

Synonyms:[(S)-5-amino-1-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}piperazine-1-carbonyl)-pentyl]-trimethyl-ammonium

Suppliers and Price of [(S)-5-amino-1-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}piperazine-1-carbonyl)-pentyl]-trimethyl-ammonium

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [(S)-5-amino-1-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}piperazine-1-carbonyl)-pentyl]-trimethyl-ammonium

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [(S)-5-amino-1-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}piperazine-1-carbonyl)-pentyl]-trimethyl-ammonium

There total 8 articles about [(S)-5-amino-1-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}piperazine-1-carbonyl)-pentyl]-trimethyl-ammonium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: [5-tert-butoxycarbonylamino-1-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}-piperazine-1-carbonyl)-pentyl]-trimethyl-ammonium

: 928851-10-9
[(S)-5-amino-1-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}piperazine-1-carbonyl)-pentyl]-trimethyl-ammonium

Guidance literature:: With trifluoroacetic acid; In dichloromethane;
DOI:10.1021/jm061143k

Reference yield:

: 188440-21-3
3-bromomethyl-2,4-dichlorobenzenesulphonyl chloride

: 928851-10-9
[(S)-5-amino-1-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}piperazine-1-carbonyl)-pentyl]-trimethyl-ammonium

Guidance literature:: Multi-step reaction with 6 steps

1.1: K₂CO₃ / dimethylformamide / 18 h / 20 °C

1.2: KI; K₂CO₃ / acetone / 7 h / Heating

2.1: LiOH; H₂O / tetrahydrofuran; methanol / 4 h / Heating

3.1: N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide; 1-hydroxybenzotriazole / CH₂Cl₂ / 1 h / cooling

3.2: diisopropylethylamine / CH₂Cl₂ / 20 °C

4.1: HCl / ethyl acetate; dioxane / 20 °C

5.1: N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide; 1-hydroxybenzotriazole / dimethylformamide / 1 h / cooling

5.2: diisopropylethylamine / dimethylformamide / 20 °C

6.1: trifluoroacetic acid / CH₂Cl₂

With hydrogenchloride; lithium hydroxide; water; potassium carbonate; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; trifluoroacetic acid; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/jm061143k

Reference yield:

: 928850-99-1
(5-tert-butoxycarbonylamino-1-carboxy-pentyl)-trimethyl-ammonium

: 928851-10-9
[(S)-5-amino-1-(4-{1-[2,4-dichloro-3-(2,4-dimethyl-quinolin-8-yloxymethyl)-benzenesulfonylamino]-cyclopentanecarbonyl}piperazine-1-carbonyl)-pentyl]-trimethyl-ammonium

Guidance literature:: Multi-step reaction with 2 steps

1.1: N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide; 1-hydroxybenzotriazole / dimethylformamide / 1 h / cooling

1.2: diisopropylethylamine / dimethylformamide / 20 °C

2.1: trifluoroacetic acid / CH₂Cl₂

With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm061143k