2-(2-Phenylethenyl)piperazine

Base Information

• Chemical Name: 2-(2-Phenylethenyl)piperazine
• CAS No.: 405872-83-5
• Molecular Formula: C₁₂H₁₆N₂
• Molecular Weight: 188.272
• DSSTox Substance ID: DTXSID30695701
• Mol file: 405872-83-5.mol

Synonyms:2-(2-phenylethenyl)piperazine;DTXSID30695701;405872-83-5

Chemical Property of 2-(2-Phenylethenyl)piperazine

Chemical Property:

• Boiling Point: 323.5±41.0 °C(Predicted)
• PKA: 9.04±0.10(Predicted)
• PSA: 24.06000
• Density: 1.096±0.06 g/cm3(Predicted)
• LogP: 1.91880
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 188.131348519
• Heavy Atom Count: 14
• Complexity: 183

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CNC(CN1)C=CC2=CC=CC=C2

Technology Process of 2-(2-Phenylethenyl)piperazine

There total 1 articles about 2-(2-Phenylethenyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

piperazine (110-85-0) + phenylacetylene (536-74-3) → 1-[(E)-2-phenylethenyl]piperazine (405872-83-5,251369-16-1) + 1,4-bis[(E)-2-phenylethenyl]piperazine

Guidance literature:

With cis-[W(CO)₄(piperidine)₂]; at 90 ℃; for 0.5h; Overall yield = 90 %Spectr.; Inert atmosphere; Schlenk technique;

DOI:10.1002/adsc.201400568

Reference yield: 75.0%

1-[(E)-2-phenylethenyl]piperazine (405872-83-5,251369-16-1) + Bromodiphenylmethane (776-74-9) → (E)-1-benzhydryl-4-styrylpiperazine dihydrochloride

Guidance literature:

With hydrogenchloride; In toluene;

DOI:10.2174/157018010792929595

Reference yield: 73.0%

1-[(E)-2-phenylethenyl]piperazine (405872-83-5,251369-16-1) + 2-chloro-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one (111631-72-2) → 2-(4-trans-cinnamylpiperazin-1-yl)-1-[3,4-dihydro-6,7-dimethoxyisoquinolin-2(1H)-yl]ethanone

Guidance literature:

With triethylamine; In dichloromethane; for 24h; Reflux;

DOI:10.1002/jhet.252

upstream raw materials:

piperazine

phenylacetylene