methyl 2-m-(2-[(2-hydroxy-3-phenoxypropyl)amino]-ethoxy)phenoxyacetate hydrochloride

Base Information

• Chemical Name: methyl 2-m-(2-[(2-hydroxy-3-phenoxypropyl)amino]-ethoxy)phenoxyacetate hydrochloride
• CAS No.: 107332-81-0
• Molecular Formula: C₂₀H₂₅NO₆*ClH
• Molecular Weight: 411.883
• Mol file: 107332-81-0.mol

Synonyms:methyl 2-m-(2-[(2-hydroxy-3-phenoxypropyl)amino]-ethoxy)phenoxyacetate hydrochloride

Chemical Property of methyl 2-m-(2-[(2-hydroxy-3-phenoxypropyl)amino]-ethoxy)phenoxyacetate hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of methyl 2-m-(2-[(2-hydroxy-3-phenoxypropyl)amino]-ethoxy)phenoxyacetate hydrochloride

There total 2 articles about methyl 2-m-(2-[(2-hydroxy-3-phenoxypropyl)amino]-ethoxy)phenoxyacetate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bromoacetic acid methyl ester (96-32-2) + N-benzyl-N-(2-m-hydroxyphenoxyethyl)-2-hydroxy-3-phenoxypropylamine (107332-79-6) → methyl 2-m-(2-[(2-hydroxy-3-phenoxypropyl)amino]-ethoxy)phenoxyacetate hydrochloride (107332-81-0)

Guidance literature:

With potassium iodide; potassium carbonate; In N-benzyl-2-(4-hydroxyphenoxy)ethylamine hydrochloride; methyl 2-m-(2-[N-benzyl-(2-hydroxy-3-phenoxypropyl)amino]ethoxy)phenoxyacetate; acetone;

Reference yield:

bromoacetic acid methyl ester (96-32-2) + N-benzyl-N-(2-m-hydroxyphenoxyethyl)-2-hydroxy-3-phenoxypropylamine (107332-79-6) + methyl 2-m-(2-[N-benzyl-(2-hydroxy-3-phenoxypropyl)amino]ethoxy)phenoxyacetate (107332-80-9) → methyl 2-m-(2-[(2-hydroxy-3-phenoxypropyl)amino]-ethoxy)phenoxyacetate hydrochloride (107332-81-0)

Guidance literature:

With potassium iodide; potassium carbonate; In acetone;

Reference yield:

methyl 2-m-(2-[(2-hydroxy-3-phenoxypropyl)amino]-ethoxy)phenoxyacetate hydrochloride (107332-81-0) → {3-[2-(2-Hydroxy-3-phenoxy-propylamino)-ethoxy]-phenoxy}-acetic acid; hydrochloride

Guidance literature:

With hydrogenchloride; at 95 - 100 ℃; for 0.5h;

DOI:10.1021/jm00088a010

upstream raw materials:

bromoacetic acid methyl ester

N-benzyl-N-(2-m-hydroxyphenoxyethyl)-2-hydroxy-3-phenoxypropylamine

methyl 2-m-(2-[N-benzyl-(2-hydroxy-3-phenoxypropyl)amino]ethoxy)phenoxyacetate