methyl 2-m-(2-[N-benzyl-(2-hydroxy-3-phenoxypropyl)amino]ethoxy)phenoxyacetate

Base Information

• Chemical Name: methyl 2-m-(2-[N-benzyl-(2-hydroxy-3-phenoxypropyl)amino]ethoxy)phenoxyacetate
• CAS No.: 107332-80-9
• Molecular Formula: C₂₇H₃₁NO₆
• Molecular Weight: 465.546

Synonyms:methyl 2-m-(2-[N-benzyl-(2-hydroxy-3-phenoxypropyl)amino]ethoxy)phenoxyacetate

Chemical Property of methyl 2-m-(2-[N-benzyl-(2-hydroxy-3-phenoxypropyl)amino]ethoxy)phenoxyacetate

Chemical Property:

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Technology Process of methyl 2-m-(2-[N-benzyl-(2-hydroxy-3-phenoxypropyl)amino]ethoxy)phenoxyacetate

There total 3 articles about methyl 2-m-(2-[N-benzyl-(2-hydroxy-3-phenoxypropyl)amino]ethoxy)phenoxyacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Phenyl glycidyl ether (122-60-1,71031-02-2) → methyl 2-m-(2-[N-benzyl-(2-hydroxy-3-phenoxypropyl)amino]ethoxy)phenoxyacetate (107332-80-9)

Guidance literature:

Multi-step reaction with 2 steps

1: propan-2-ol / 72 h / Heating

2: K₂CO₃, KI / acetone / 24 h / Heating

With potassium carbonate; potassium iodide; In isopropyl alcohol; acetone;

DOI:10.1021/jm00088a010

Reference yield:

N-benzyl-2-(3-hydroxyphenoxy)ethylamine hydrochloride (107332-84-3) → methyl 2-m-(2-[N-benzyl-(2-hydroxy-3-phenoxypropyl)amino]ethoxy)phenoxyacetate (107332-80-9)

Guidance literature:

Multi-step reaction with 2 steps

1: propan-2-ol / 72 h / Heating

2: K₂CO₃, KI / acetone / 24 h / Heating

With potassium carbonate; potassium iodide; In isopropyl alcohol; acetone;

DOI:10.1021/jm00088a010

Reference yield:

bromoacetic acid methyl ester (96-32-2) + N-benzyl-N-(2-m-hydroxyphenoxyethyl)-2-hydroxy-3-phenoxypropylamine (107332-79-6) → methyl 2-m-(2-[N-benzyl-(2-hydroxy-3-phenoxypropyl)amino]ethoxy)phenoxyacetate (107332-80-9)

Guidance literature:

With potassium carbonate; potassium iodide; In acetone; for 24h; Heating;

DOI:10.1021/jm00088a010

upstream raw materials:

bromoacetic acid methyl ester

N-benzyl-N-(2-m-hydroxyphenoxyethyl)-2-hydroxy-3-phenoxypropylamine

Phenyl glycidyl ether

N-benzyl-2-(3-hydroxyphenoxy)ethylamine hydrochloride

Downstream raw materials:

{3-[2-(2-Hydroxy-3-phenoxy-propylamino)-ethoxy]-phenoxy}-acetic acid methyl ester

methyl 2-m-(2-[(2-hydroxy-3-phenoxypropyl)amino]-ethoxy)phenoxyacetate hydrochloride

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