dimethyl 2-benzyl-5-(3-isocyanatopropyl)-6-methoxypyridine-3,4-dicarboxylate

Base Information

Chemical Name:dimethyl 2-benzyl-5-(3-isocyanatopropyl)-6-methoxypyridine-3,4-dicarboxylate
CAS No.:1549877-25-9
Molecular Formula:C₂₁H₂₂N₂O₆
Molecular Weight:398.415
Hs Code.:

Synonyms:dimethyl 2-benzyl-5-(3-isocyanatopropyl)-6-methoxypyridine-3,4-dicarboxylate

Suppliers and Price of dimethyl 2-benzyl-5-(3-isocyanatopropyl)-6-methoxypyridine-3,4-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of dimethyl 2-benzyl-5-(3-isocyanatopropyl)-6-methoxypyridine-3,4-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of dimethyl 2-benzyl-5-(3-isocyanatopropyl)-6-methoxypyridine-3,4-dicarboxylate

There total 6 articles about dimethyl 2-benzyl-5-(3-isocyanatopropyl)-6-methoxypyridine-3,4-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 1482501-69-8
dimethyl 6-benzyl-9-methoxy-5-oxo-2,3,5,6-tetrahydro-1H-6,8a-(azenometheno)indolizine-7,8-dicarboxylate

: 1549877-25-9
dimethyl 2-benzyl-5-(3-isocyanatopropyl)-6-methoxypyridine-3,4-dicarboxylate

Guidance literature:: In toluene; for 1h; Inert atmosphere; Microwave irradiation;
DOI:10.1021/ol403632t

Reference yield:

: 38074-72-5
(S)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid methyl ester

: 1549877-25-9
dimethyl 2-benzyl-5-(3-isocyanatopropyl)-6-methoxypyridine-3,4-dicarboxylate

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium azide / butanone / 72 h / 80 °C / Inert atmosphere

2.1: triphenylphosphine / toluene / 19 h / 20 - 90 °C / Inert atmosphere

3.1: lithium hexamethyldisilazane / toluene; tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

3.2: 0.33 h / -78 °C / Inert atmosphere

4.1: N,N-dimethyl-formamide / 16 h / 60 °C / Inert atmosphere

5.1: toluene / 1 h / Inert atmosphere; Microwave irradiation

With sodium azide; triphenylphosphine; lithium hexamethyldisilazane; In tetrahydrofuran; N,N-dimethyl-formamide; toluene; butanone;
DOI:10.1021/ol403632t

Reference yield:

: 914468-21-6
N-(azidoacetyl)-L-proline methyl ester

: 1549877-25-9
dimethyl 2-benzyl-5-(3-isocyanatopropyl)-6-methoxypyridine-3,4-dicarboxylate

Guidance literature:: Multi-step reaction with 4 steps

1.1: triphenylphosphine / toluene / 19 h / 20 - 90 °C / Inert atmosphere

2.1: lithium hexamethyldisilazane / toluene; tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

2.2: 0.33 h / -78 °C / Inert atmosphere

3.1: N,N-dimethyl-formamide / 16 h / 60 °C / Inert atmosphere

4.1: toluene / 1 h / Inert atmosphere; Microwave irradiation

With triphenylphosphine; lithium hexamethyldisilazane; In tetrahydrofuran; N,N-dimethyl-formamide; toluene;
DOI:10.1021/ol403632t