Cyclopropane, 1-(5-hexen-1-ynyl)-2-methyl-, (1R,2R)-rel- (9CI)

Base Information

Chemical Name:Cyclopropane, 1-(5-hexen-1-ynyl)-2-methyl-, (1R,2R)-rel- (9CI)
CAS No.:403611-08-5
Molecular Formula:C₁₀H₁₄
Molecular Weight:134.221
Hs Code.:
Mol file:403611-08-5.mol

Synonyms:Cyclopropane,1-(5-hexen-1-ynyl)-2-methyl-, (1R,2R)-rel- (9CI)

Suppliers and Price of Cyclopropane, 1-(5-hexen-1-ynyl)-2-methyl-, (1R,2R)-rel- (9CI)

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Cyclopropane, 1-(5-hexen-1-ynyl)-2-methyl-, (1R,2R)-rel- (9CI)

Chemical Property:

PSA：0.00000
LogP:0.00000

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of Cyclopropane, 1-(5-hexen-1-ynyl)-2-methyl-, (1R,2R)-rel- (9CI)

There total 5 articles about Cyclopropane, 1-(5-hexen-1-ynyl)-2-methyl-, (1R,2R)-rel- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

: 5162-44-7
1-bromo-4-butene

: 52114-14-4,52114-15-5,122519-94-2,135214-27-6
trans-(2-Methylcyclopropyl)acetylene

: 403611-08-5
5-trans-(2-methylcyclopropyl)hex-1-en-5-yne

Guidance literature:: With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; In tetrahydrofuran; hexane; at 15 - 20 ℃; for 3h;
DOI:10.1002/1099-0690(200111)2001:21<4009::AID-EJOC4009>3.0.CO;2-4

Reference yield:

: 102438-65-3
2-chlorohexan-5-one

: 403611-08-5
5-trans-(2-methylcyclopropyl)hex-1-en-5-yne

Guidance literature:: Multi-step reaction with 4 steps

1: 73 percent / potassium tert-butoxide / diethyl ether / 0.25 h / Heating

2: 38 percent / phosphorous pentachloride / CCl₄ / 5 h / 0 - 5 °C

3: 61 percent / potassium tert-butoxide; 18-crown-6 / pentane / 18 h / 20 °C

4: 10 percent / n-butyllithium; HMPTA / hexane; tetrahydrofuran / 3 h / 15 - 20 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; 18-crown-6 ether; phosphorus pentachloride; potassium tert-butylate; In tetrahydrofuran; tetrachloromethane; diethyl ether; hexane; pentane;
DOI:10.1002/1099-0690(200111)2001:21<4009::AID-EJOC4009>3.0.CO;2-4

Reference yield:

: 3620-18-6
3-acetyl-5-methyldihydrofuran-2(3H)-one

: 403611-08-5
5-trans-(2-methylcyclopropyl)hex-1-en-5-yne

Guidance literature:: Multi-step reaction with 5 steps

1: 42 percent / benzyltriethylammonium chloride; HCl; water / CH₂Cl₂ / 18 h / 20 °C

2: 73 percent / potassium tert-butoxide / diethyl ether / 0.25 h / Heating

3: 38 percent / phosphorous pentachloride / CCl₄ / 5 h / 0 - 5 °C

4: 61 percent / potassium tert-butoxide; 18-crown-6 / pentane / 18 h / 20 °C

5: 10 percent / n-butyllithium; HMPTA / hexane; tetrahydrofuran / 3 h / 15 - 20 °C

With hydrogenchloride; N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; 18-crown-6 ether; phosphorus pentachloride; potassium tert-butylate; N-benzyl-N,N,N-triethylammonium chloride; water; In tetrahydrofuran; tetrachloromethane; diethyl ether; hexane; dichloromethane; pentane;
DOI:10.1002/1099-0690(200111)2001:21<4009::AID-EJOC4009>3.0.CO;2-4