(2R,3R)-3-(3,5-difluorophenyl)glycidol

Base Information

Chemical Name:(2R,3R)-3-(3,5-difluorophenyl)glycidol
CAS No.:866209-32-7
Molecular Formula:C₉H₈F₂O₂
Molecular Weight:186.158
Hs Code.:

Synonyms:(2R,3R)-3-(3,5-difluorophenyl)glycidol

Suppliers and Price of (2R,3R)-3-(3,5-difluorophenyl)glycidol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,3R)-3-(3,5-difluorophenyl)glycidol

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Technology Process of (2R,3R)-3-(3,5-difluorophenyl)glycidol

There total 3 articles about (2R,3R)-3-(3,5-difluorophenyl)glycidol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 405937-98-6
(E)-3-(3,5-difluorophenyl)prop-2-en-1-ol

: 866209-32-7
(2R,3R)-3-(3,5-difluorophenyl)glycidol

Guidance literature:: (E)-3-(3,5-difluorophenyl)prop-2-en-1-ol; With titanium(IV) isopropylate; tert.-butylhydroperoxide; D-(-)-diisopropyl tartrate; In dichloromethane; at -25 ℃; Molecular sieve; Inert atmosphere;

With sodium chloride; sodium hydroxide; In diethyl ether; dichloromethane; at -25 - 5 ℃; Molecular sieve; Inert atmosphere;
DOI:10.1021/jm901559e

Reference yield: 70.0%

: 866209-32-7
(2R,3R)-3-(3,5-difluorophenyl)glycidol

Guidance literature:

Reference yield:

: 3-(3,5-difluorophenyl)prop-2-en-1-ol

: 866209-32-7
(2R,3R)-3-(3,5-difluorophenyl)glycidol

Guidance literature:: 3-(3,5-difluorophenyl)prop-2-en-1-ol; titanium(IV) isopropylate; D-(-)-diisopropyl tartrate; In toluene; at -35 ℃; for 0.5h; Molecular sieve;

With tert.-butylhydroperoxide; In decane; toluene; at -35 - -25 ℃; for 14h;