2-Benzoylamino-3-cyano-2-ethoxycarbonyl-succinic acid 1-ethyl ester 4-methyl ester

Base Information

Chemical Name:2-Benzoylamino-3-cyano-2-ethoxycarbonyl-succinic acid 1-ethyl ester 4-methyl ester
CAS No.:81917-98-8
Molecular Formula:C₁₈H₂₀N₂O₇
Molecular Weight:376.366
Hs Code.:

Synonyms:2-Benzoylamino-3-cyano-2-ethoxycarbonyl-succinic acid 1-ethyl ester 4-methyl ester

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Chemical Property of 2-Benzoylamino-3-cyano-2-ethoxycarbonyl-succinic acid 1-ethyl ester 4-methyl ester

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Technology Process of 2-Benzoylamino-3-cyano-2-ethoxycarbonyl-succinic acid 1-ethyl ester 4-methyl ester

There total 3 articles about 2-Benzoylamino-3-cyano-2-ethoxycarbonyl-succinic acid 1-ethyl ester 4-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 81918-05-0
2-Benzoylimino-malonic acid diethyl ester

: 105-34-0
methyl 2-cyanoacetate

: 81917-98-8
2-Benzoylamino-3-cyano-2-ethoxycarbonyl-succinic acid 1-ethyl ester 4-methyl ester

Guidance literature:: With base; In tetrahydrofuran;

Reference yield:

: 96-86-6
diethyl benzamidomalonate

: 81917-98-8
2-Benzoylamino-3-cyano-2-ethoxycarbonyl-succinic acid 1-ethyl ester 4-methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: Br₂ / CCl₄

2: Huenig-Base / tetrahydrofuran

3: 92 percent / base / tetrahydrofuran

With bromine; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; tetrachloromethane;

Reference yield:

: 81918-02-7
2-Benzoylamino-2-brommalonsaeure-diethylester

: 81917-98-8
2-Benzoylamino-3-cyano-2-ethoxycarbonyl-succinic acid 1-ethyl ester 4-methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: Huenig-Base / tetrahydrofuran

2: 92 percent / base / tetrahydrofuran

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran;