(3'R,4S)-3-{4-tert-butoxycarbonyl-3-(4-fluorophenyl)-1-oxobutyl}-5,5-di(2-methoxy-5-methylphenyl)-4-isopropyloxazolidin-2-one

Base Information

Chemical Name:(3'R,4S)-3-{4-tert-butoxycarbonyl-3-(4-fluorophenyl)-1-oxobutyl}-5,5-di(2-methoxy-5-methylphenyl)-4-isopropyloxazolidin-2-one
CAS No.:1130247-41-4
Molecular Formula:C₃₇H₄₄FNO₇
Molecular Weight:633.757
Hs Code.:

Synonyms:(3'R,4S)-3-{4-tert-butoxycarbonyl-3-(4-fluorophenyl)-1-oxobutyl}-5,5-di(2-methoxy-5-methylphenyl)-4-isopropyloxazolidin-2-one

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Chemical Property of (3'R,4S)-3-{4-tert-butoxycarbonyl-3-(4-fluorophenyl)-1-oxobutyl}-5,5-di(2-methoxy-5-methylphenyl)-4-isopropyloxazolidin-2-one

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Technology Process of (3'R,4S)-3-{4-tert-butoxycarbonyl-3-(4-fluorophenyl)-1-oxobutyl}-5,5-di(2-methoxy-5-methylphenyl)-4-isopropyloxazolidin-2-one

There total 1 articles about (3'R,4S)-3-{4-tert-butoxycarbonyl-3-(4-fluorophenyl)-1-oxobutyl}-5,5-di(2-methoxy-5-methylphenyl)-4-isopropyloxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₃₃H₃₅ClFNO₆

: 75-65-0
tert-butyl alcohol

: 1130247-41-4
(3'R,4S)-3-{4-tert-butoxycarbonyl-3-(4-fluorophenyl)-1-oxobutyl}-5,5-di(2-methoxy-5-methylphenyl)-4-isopropyloxazolidin-2-one

Guidance literature:: With dmap; at 20 ℃; Inert atmosphere; Cooling with ice;
DOI:10.1016/j.tetasy.2008.12.010

Reference yield: 93.0%

: 1130247-41-4
(3'R,4S)-3-{4-tert-butoxycarbonyl-3-(4-fluorophenyl)-1-oxobutyl}-5,5-di(2-methoxy-5-methylphenyl)-4-isopropyloxazolidin-2-one

: C₁₅H₁₉FO₄

: 1130246-56-8
(4S)-5,5-di(2-methoxy-5-methylphenyl)-4-isopropyloxazolidin-2-one

Guidance literature:: (3'R,4S)-3-{4-tert-butoxycarbonyl-3-(4-fluorophenyl)-1-oxobutyl}-5,5-di(2-methoxy-5-methylphenyl)-4-isopropyloxazolidin-2-one; With sodium hydroxide; water; In tetrahydrofuran; methanol; at 20 ℃; for 2.5h; Inert atmosphere;

With hydrogenchloride; In water; Inert atmosphere;
DOI:10.1016/j.tetasy.2008.12.010