methyl 2-(2,4-dioxo-5,5-diphenyl-1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)imidazolidin-3-yl)acetate hydrochloride

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Chemical Name:methyl 2-(2,4-dioxo-5,5-diphenyl-1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)imidazolidin-3-yl)acetate hydrochloride
CAS No.:1370333-50-8
Molecular Formula:C₃₃H₃₈N₄O₅*ClH
Molecular Weight:607.149
Hs Code.:

Synonyms:methyl 2-(2,4-dioxo-5,5-diphenyl-1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)imidazolidin-3-yl)acetate hydrochloride

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Chemical Property of methyl 2-(2,4-dioxo-5,5-diphenyl-1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)imidazolidin-3-yl)acetate hydrochloride

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Technology Process of methyl 2-(2,4-dioxo-5,5-diphenyl-1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)imidazolidin-3-yl)acetate hydrochloride

There total 2 articles about methyl 2-(2,4-dioxo-5,5-diphenyl-1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)imidazolidin-3-yl)acetate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 1350707-12-8
methyl 2-(3-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2,5-dioxo-4,4-diphenylimidazolidin-1-yl)acetate

: 1370333-50-8
methyl 2-(2,4-dioxo-5,5-diphenyl-1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)imidazolidin-3-yl)acetate hydrochloride

Guidance literature:: With hydrogenchloride; In methanol; at 4 ℃;
DOI:10.1016/j.bmc.2012.02.009

Reference yield:

: 35386-24-4
1-(2-Methoxyphenyl)piperazine

: 1350706-97-6
methyl 2-(3-(4-bromobutyl)-2,5-dioxo-4,4-diphenylimidazolidin-1-yl)acetate

: 1370333-50-8
methyl 2-(2,4-dioxo-5,5-diphenyl-1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)imidazolidin-3-yl)acetate hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate / acetone / 0.5 h / Reflux

1.2: 96 h / 20 °C

2.1: hydrogenchloride / methanol / 4 °C

With hydrogenchloride; N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate; In methanol; acetone;
DOI:10.1016/j.bmc.2012.02.009