2-bromo-N-(3-chlorophenyl)propanamide

Base Information

• Chemical Name: 2-bromo-N-(3-chlorophenyl)propanamide
• CAS No.: 77112-27-7
• Molecular Formula: C₉H₉BrClNO
• Molecular Weight: 262.534
• DSSTox Substance ID: DTXSID301286612

Synonyms:2-bromo-N-(3-chlorophenyl)propanamide;77112-27-7;starbld0031301;DTXSID301286612;MFCD03014412;AKOS022340761;CS-0365334

Chemical Property of 2-bromo-N-(3-chlorophenyl)propanamide

Chemical Property:

• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 260.95560
• Heavy Atom Count: 13
• Complexity: 189

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C(=O)NC1=CC(=CC=C1)Cl)Br

Technology Process of 2-bromo-N-(3-chlorophenyl)propanamide

There total 3 articles about 2-bromo-N-(3-chlorophenyl)propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-chloro-aniline (108-42-9) + 2-Bromopropionyl chloride (7148-74-5) → α-bromo-N-(3-chlorophenyl)propionamide (77112-27-7)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 20h; Reflux;

DOI:10.1055/s-0033-1338703

Reference yield:

α-bromopropionyl bromide (563-76-8) + 3-chloro-aniline (108-42-9) → α-bromo-N-(3-chlorophenyl)propionamide (77112-27-7)

Guidance literature:

With triethylamine; In chloroform;

DOI:10.1007/s12272-012-0805-4

Reference yield:

→ α-bromo-N-(3-chlorophenyl)propionamide (77112-27-7)

Guidance literature:

3-Chlor-anilin, 2-Brom-propionylbromid, Eg., wss. Natriumacetat-Lsg., Kuehlung;

upstream raw materials:

α-bromopropionyl bromide

3-chloro-aniline

2-Bromopropionyl chloride

Downstream raw materials:

N-(3-chloro-phenyl)-2-morpholin-4-yl-propionamide

N-(3-chlorophenyl)-2-(1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-ylsulfanyl)propionamide

C₁₅H₁₄ClNO₂

1-(3-chloro-phenyl)-3-[2-(3,3-dipropyl-azetidin-1-yl)-1-methyl-ethyl]-4-methyl-imidazolidin-2-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 77112-27-7 α-bromo-N-(3-chlorophenyl)propionamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send