2-Cyclopenten-1-one,5-ethylidene-2-hydroxy-3,4-dimethyl-,(5Z)-(9CI)

Base Information

• Chemical Name: 2-Cyclopenten-1-one,5-ethylidene-2-hydroxy-3,4-dimethyl-,(5Z)-(9CI)
• CAS No.: 353475-98-6
• Molecular Formula: C₉H₁₂O₂
• Molecular Weight: 152.193
• Mol file: 353475-98-6.mol

Synonyms:2-Cyclopenten-1-one,5-ethylidene-2-hydroxy-3,4-dimethyl-,(5Z)-(9CI)

Chemical Property of 2-Cyclopenten-1-one,5-ethylidene-2-hydroxy-3,4-dimethyl-,(5Z)-(9CI)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Cyclopenten-1-one,5-ethylidene-2-hydroxy-3,4-dimethyl-,(5Z)-(9CI)

There total 3 articles about 2-Cyclopenten-1-one,5-ethylidene-2-hydroxy-3,4-dimethyl-,(5Z)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

1-(methoxymethoxy)-1,2-propadiene (91299-17-1) + 4-[(2E)-1-oxo-2-methyl-2-butenyl]morpholine (212518-27-9) + methyl iodide (74-88-4) → (5E)-5-ethylidene-2-hydroxy-3,4-dimethylcyclopent-2-enone (462116-79-6,353475-98-6)

Guidance literature:

Multistep reaction;

DOI:10.1016/j.tet.2005.01.097

Reference yield:

Tiglic acid (80-59-1) → (5E)-5-ethylidene-2-hydroxy-3,4-dimethylcyclopent-2-enone (462116-79-6,353475-98-6)

Guidance literature:

Multi-step reaction with 3 steps

1: oxalyl chloride; DMF

2: pyridine

With pyridine; oxalyl dichloride; N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2005.01.097

Reference yield:

(E)-2-methylbut-2-enoyl chloride (35660-94-7) → (5E)-5-ethylidene-2-hydroxy-3,4-dimethylcyclopent-2-enone (462116-79-6,353475-98-6)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine

With pyridine;

DOI:10.1016/j.tet.2005.01.097

upstream raw materials:

1-(methoxymethoxy)-1,2-propadiene

4-[(2E)-1-oxo-2-methyl-2-butenyl]morpholine

methyl iodide

Tiglic acid