tert-butyl diphenyl(2-((4R,5R)-2,2,5-trimethyl-1,3-dioxolan-4-yl)ethoxy)silane

Base Information

• Chemical Name: tert-butyl diphenyl(2-((4R,5R)-2,2,5-trimethyl-1,3-dioxolan-4-yl)ethoxy)silane
• CAS No.: 1449467-80-4
• Molecular Formula: C₂₄H₃₄O₃Si
• Molecular Weight: 398.618
• Mol file: 1449467-80-4.mol

Synonyms:tert-butyl diphenyl(2-((4R,5R)-2,2,5-trimethyl-1,3-dioxolan-4-yl)ethoxy)silane

Chemical Property of tert-butyl diphenyl(2-((4R,5R)-2,2,5-trimethyl-1,3-dioxolan-4-yl)ethoxy)silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl diphenyl(2-((4R,5R)-2,2,5-trimethyl-1,3-dioxolan-4-yl)ethoxy)silane

There total 4 articles about tert-butyl diphenyl(2-((4R,5R)-2,2,5-trimethyl-1,3-dioxolan-4-yl)ethoxy)silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(2R,3R)-5-(tert-butyl diphenylsilyloxy)pentane-2,3-diol (1449467-79-1) + 2,2-dimethoxy-propane (77-76-9) → tert-butyl diphenyl(2-((4R,5R)-2,2,5-trimethyl-1,3-dioxolan-4-yl)ethoxy)silane (1449467-80-4)

Guidance literature:

With toluene-4-sulfonic acid; In water; acetone; at 20 ℃;

Reference yield:

(E)-3-penten-1-ol (764-37-4) → tert-butyl diphenyl(2-((4R,5R)-2,2,5-trimethyl-1,3-dioxolan-4-yl)ethoxy)silane (1449467-80-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 1H-imidazole / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

2: AD-mix-β; methanesulfonamide; water / tert-butyl alcohol / 48 h / 0 °C / Inert atmosphere

3: toluene-4-sulfonic acid / acetone / 20 °C / Inert atmosphere

With 1H-imidazole; methanesulfonamide; AD-mix-β; water; toluene-4-sulfonic acid; In N,N-dimethyl-formamide; acetone; tert-butyl alcohol;

DOI:10.1002/ejoc.201201338

Reference yield:

(E)-tert-butyl (pent-3-enyloxy)diphenylsilane (124070-55-9) → tert-butyl diphenyl(2-((4R,5R)-2,2,5-trimethyl-1,3-dioxolan-4-yl)ethoxy)silane (1449467-80-4)

Guidance literature:

Multi-step reaction with 2 steps

1: methanesulfonamide; (DHQD)₂PHAL / water; tert-butyl alcohol / 48 h / 0 °C

2: toluene-4-sulfonic acid / water; acetone / 20 °C

With methanesulfonamide; (DHQD)₂PHAL; toluene-4-sulfonic acid; In water; acetone; tert-butyl alcohol;

upstream raw materials:

(E)-3-penten-1-ol

(2R,3R)-5-(tert-butyl diphenylsilyloxy)pentane-2,3-diol

2,2-dimethoxy-propane

(E)-tert-butyl (pent-3-enyloxy)diphenylsilane

Downstream raw materials:

C₃₄H₅₀O₇Si