4-Chloro-8-iodoquinoline

Base Information

Chemical Name:4-Chloro-8-iodoquinoline
CAS No.:49713-55-5
Molecular Formula:C9H5 Cl I N
Molecular Weight:289.5
Hs Code.:
European Community (EC) Number:867-689-5
DSSTox Substance ID:DTXSID40496605
Wikidata:Q82345579
Mol file:49713-55-5.mol

Synonyms:4-CHLORO-8-IODOQUINOLINE;49713-55-5;4-chloro-8-iodo-quinoline;SCHEMBL1245479;DTXSID40496605;JMDRQEKDXIQUBD-UHFFFAOYSA-N;AT26623;Methyl?2-(piperazin-1-yl)ethylcarbamate;CS-0257785;EN300-67730

Suppliers and Price of 4-Chloro-8-iodoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemcia Scientific
4-Chloro-8-iodo-quinoline 95%
1 G
$ 295.00

Total 3 raw suppliers

Chemical Property of 4-Chloro-8-iodoquinoline

Chemical Property:

PSA：12.89000
LogP:3.49280
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:288.91552
Heavy Atom Count:12
Complexity:165

Purity/Quality:

99% ^*data from raw suppliers

4-Chloro-8-iodo-quinoline 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=CN=C2C(=C1)I)Cl

Technology Process of 4-Chloro-8-iodoquinoline

There total 7 articles about 4-Chloro-8-iodoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 49713-50-0,832717-35-8
8-iodoquinolin-4(1H)-one

: 49713-55-5
4-chloro-8-iodoquinoline

Guidance literature:: With trichlorophosphate; N,N-dimethyl-formamide; for 1h; Heating / reflux;

Reference yield: 39.0%

: 81764-16-1
4-chloro-8-aminoquinoline

: 49713-55-5
4-chloro-8-iodoquinoline

Guidance literature:: 4-chloro-8-aminoquinoline; With hydrogenchloride; sodium nitrite; In methanol; water; for 0.166667h; Cooling;

With copper(l) iodide; hydrogen iodide; In methanol; water; at 20 ℃; for 0.0833333h;
DOI:10.1021/acs.joc.0c00658

Reference yield:

: 5-{[(2-iodophenyl)amino]methylene}-2,2-dimethyl-1,3-dioxane-4,6-dione

: 49713-55-5
4-chloro-8-iodoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: diphenylether / 0.58 h / 210 °C

2: trichlorophosphate / 1.5 h / 105 °C

With trichlorophosphate; In diphenylether;
DOI:10.1021/jacs.1c07354