(1Z)-1,3-diphenyl-2-propyn-1-one O-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]oxime

Base Information

• Chemical Name: (1Z)-1,3-diphenyl-2-propyn-1-one O-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]oxime
• CAS No.: 1227781-90-9
• Molecular Formula: C₂₅H₃₁NO₂Si
• Molecular Weight: 405.612
• Mol file: 1227781-90-9.mol

Synonyms:(1Z)-1,3-diphenyl-2-propyn-1-one O-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]oxime

Chemical Property of (1Z)-1,3-diphenyl-2-propyn-1-one O-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]oxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1Z)-1,3-diphenyl-2-propyn-1-one O-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]oxime

There total 1 articles about (1Z)-1,3-diphenyl-2-propyn-1-one O-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

C10H23NO2Si (1227782-16-2) + 1,3-diphenyl-2-propynone (7338-94-5) → (1Z)-1,3-diphenyl-2-propyn-1-one O-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]oxime (1227781-90-9)

Guidance literature:

With pyridinium p-toluenesulfonate; In ethanol; for 12h; Reflux;

DOI:10.1021/ol100803e

Reference yield: 80.0%

(1Z)-1,3-diphenyl-2-propyn-1-one O-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]oxime (1227781-90-9) → 5-(4-methoxyphenyl)-3-phenyl-4-(2-propen-1-yl)isoxazole (1227781-93-2) + 4-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]-3,5-diphenylisoxazole (1227782-08-2)

Guidance literature:

With gold(III) chloride; In trans-1,2-dichloroethylene; Inert atmosphere;

DOI:10.1021/ol100803e

Reference yield: 77.0%

(1Z)-1,3-diphenyl-2-propyn-1-one O-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]oxime (1227781-90-9) → 4-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]-3,5-diphenylisoxazole (1227782-08-2)

Guidance literature:

With gold(III) chloride; In trans-1,2-dichloroethylene; at 20 ℃; regioselective reaction; Inert atmosphere; Reflux;

DOI:10.1021/ol100803e

upstream raw materials:

C₁₀H₂₃NO₂Si

1,3-diphenyl-2-propynone

Downstream raw materials:

5-(4-methoxyphenyl)-3-phenyl-4-(2-propen-1-yl)isoxazole

4-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]-3,5-diphenylisoxazole