4-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]-3,5-diphenylisoxazole

Base Information

• Chemical Name: 4-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]-3,5-diphenylisoxazole
• CAS No.: 1227782-08-2
• Molecular Formula: C₂₅H₃₁NO₂Si
• Molecular Weight: 405.612
• Mol file: 1227782-08-2.mol

Synonyms:4-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]-3,5-diphenylisoxazole

Chemical Property of 4-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]-3,5-diphenylisoxazole

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 4-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]-3,5-diphenylisoxazole

There total 2 articles about 4-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]-3,5-diphenylisoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

(1Z)-1,3-diphenyl-2-propyn-1-one O-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]oxime (1227781-90-9) → 5-(4-methoxyphenyl)-3-phenyl-4-(2-propen-1-yl)isoxazole (1227781-93-2) + 4-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]-3,5-diphenylisoxazole (1227782-08-2)

Guidance literature:

With gold(III) chloride; In trans-1,2-dichloroethylene; Inert atmosphere;

DOI:10.1021/ol100803e

Reference yield: 77.0%

(1Z)-1,3-diphenyl-2-propyn-1-one O-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]oxime (1227781-90-9) → 4-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]-3,5-diphenylisoxazole (1227782-08-2)

Guidance literature:

With gold(III) chloride; In trans-1,2-dichloroethylene; at 20 ℃; regioselective reaction; Inert atmosphere; Reflux;

DOI:10.1021/ol100803e

upstream raw materials:

(1Z)-1,3-diphenyl-2-propyn-1-one O-[[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2-propen-1-yl]oxime