Technology Process of C24H29N7O5
There total 8 articles about C24H29N7O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
7-[4-(3-azido-5-methoxybenzyloxy)phenylcarbamoyl]heptanoic acid;
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
dichloromethane;
for 1h;
2-azidoethanol;
With
N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
at 0 ℃;
for 12h;
DOI:10.1016/j.bmcl.2012.08.104
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C
2.1: palladium 10% on activated carbon; methanol / 20 °C
3.1: potassium carbonate / acetone / 12 h / Reflux
4.1: potassium hydroxide; methanol / tetrahydrofuran / 24 h / 20 °C
5.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 1 h
5.2: 12 h / 0 °C
With
methanol; palladium 10% on activated carbon; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; potassium hydroxide;
In
tetrahydrofuran; dichloromethane; acetone;
DOI:10.1016/j.bmcl.2012.08.104
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C
2.1: sodium nitrite; sodium azide / water / 5 h / 0 - 20 °C
3.1: triethylamine / dichloromethane / 0.5 h / 0 °C
4.1: potassium carbonate / acetone / 12 h / Reflux
5.1: potassium hydroxide; methanol / tetrahydrofuran / 24 h / 20 °C
6.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 1 h
6.2: 12 h / 0 °C
With
methanol; lithium aluminium tetrahydride; sodium azide; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; potassium hydroxide; sodium nitrite;
In
tetrahydrofuran; dichloromethane; water; acetone;
DOI:10.1016/j.bmcl.2012.08.104
