3-(4-Chlorophenyl)-2-hydroxypropionic acid

Base Information

Chemical Name:3-(4-Chlorophenyl)-2-hydroxypropionic acid
CAS No.:23434-95-9
Molecular Formula:C₉H₉ClO₃
Molecular Weight:200.622
Hs Code.:2918199890
European Community (EC) Number:830-082-0
DSSTox Substance ID:DTXSID501279823

Synonyms:3-(4-chlorophenyl)-2-hydroxypropionic acid;23434-95-9;3-(4-chlorophenyl)-2-hydroxypropanoic acid;MFCD11935789;Benzenepropanoic acid, 4-chloro-alpha-hydroxy-;SCHEMBL2459377;HWVHXAYPEXNZSZ-UHFFFAOYSA-N;DTXSID501279823;YAA43495;AC1675;AKOS015150547;AC-29812;CS-12033;SY036070;3-(4-chlorophenyl)-2-hydroxypropionicacid;CS-0210444;EN300-319197;A918721;beta-(4-chlorophenyl)-alpha-hydroxylpropionic Acid

Suppliers and Price of 3-(4-Chlorophenyl)-2-hydroxypropionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
3-(4-Chlorophenyl)-2-hydroxypropionic acid
5 g
$ 1322.00

SynQuest Laboratories
3-(4-Chlorophenyl)-2-hydroxypropionic acid
1 g
$ 493.00

Crysdot
3-(4-Chlorophenyl)-2-hydroxypropionicAcid 95+%
5g
$ 465.00

Alichem
3-(4-Chlorophenyl)-2-hydroxypropionicAcid
5g
$ 460.60

AK Scientific
3-(4-Chlorophenyl)-2-hydroxypropionicacid
5g
$ 694.00

Total 6 raw suppliers

Chemical Property of 3-(4-Chlorophenyl)-2-hydroxypropionic acid

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:200.0240218
Heavy Atom Count:13
Complexity:176

Purity/Quality:

97% ^*data from raw suppliers

3-(4-Chlorophenyl)-2-hydroxypropionic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1CC(C(=O)O)O)Cl

Technology Process of 3-(4-Chlorophenyl)-2-hydroxypropionic acid

There total 8 articles about 3-(4-Chlorophenyl)-2-hydroxypropionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 3617-01-4
β-(4-chlorophenyl)pyruvic acid

: 23434-95-9
3-(p-Chlorophenyl)-2-hydroxypropanoic acid

Guidance literature:: With sodium hydroxide; sodium tetrahydroborate; at 5 - 10 ℃;
DOI:10.1016/j.tet.2005.09.104

Reference yield: 18.0%

: 7424-00-2,1991-78-2
DL-Phe(4Cl)

: 23434-95-9
3-(p-Chlorophenyl)-2-hydroxypropanoic acid

Guidance literature:: With sulfuric acid; water; sodium nitrite; at 0 - 20 ℃;

Reference yield:

: 104-88-1
4-chlorobenzaldehyde

: 23434-95-9
3-(p-Chlorophenyl)-2-hydroxypropanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 94 percent / acetic anhydride; sodium acetate / 0.07 h / microwave irradiation

2: aq. HCl / Heating

3: 82 percent / aq. NaOH; NaBH₄ / 5 - 10 °C

With hydrogenchloride; sodium hydroxide; sodium tetrahydroborate; sodium acetate; acetic anhydride;
DOI:10.1016/j.tet.2005.09.104