C₃₆H₄₅IN₂O₈

Base Information

• Chemical Name: C₃₆H₄₅IN₂O₈
• CAS No.: 1399009-21-2
• Molecular Formula: C₃₆H₄₅IN₂O₈
• Molecular Weight: 760.666
• Mol file: 1399009-21-2.mol

Synonyms:C₃₆H₄₅IN₂O₈

Chemical Property of C₃₆H₄₅IN₂O₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of C₃₆H₄₅IN₂O₈

There total 5 articles about C₃₆H₄₅IN₂O₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

peracetic acid (79-21-0) + N,N'-(2S,2'S)-2,2'-(2-iodo-1,3-phenylene)bis(oxy)bis(propane-2,1-diyl)bis(2,4,6-trimethylbenzamide) (1399008-27-5) → C36H45IN2O8 (1399009-21-2)

Guidance literature:

With acetic acid; at 25 ℃; for 9h;

DOI:10.1002/anie.201303559

Reference yield: 99.0%

N,N'-(2S,2'S)-2,2'-(2-iodo-1,3-phenylene)bis(oxy)bis(propane-2,1-diyl)bis(2,4,6-trimethylbenzamide) (1399008-27-5) + acetic acid (64-19-7,77671-22-8) → C36H45IN2O8 (1399009-21-2)

Guidance literature:

With Selectfluor; In acetonitrile; at 25 ℃; for 2h;

DOI:10.1002/anie.201303559

Reference yield:

2-iodoresorcinol (41046-67-7) → C36H45IN2O8 (1399009-21-2)

Guidance literature:

Multi-step reaction with 4 steps

1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran; toluene / 12 h / 0 - 25 °C

2: trifluoroacetic acid / dichloromethane / 8 h / 25 °C

3: pyridine / dichloromethane / 12 h / 0 - 25 °C

4: acetic acid / 9 h / 25 °C

With pyridine; di-isopropyl azodicarboxylate; acetic acid; triphenylphosphine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; toluene;

DOI:10.1002/anie.201303559

upstream raw materials:

N,N'-(2S,2'S)-2,2'-(2-iodo-1,3-phenylene)bis(oxy)bis(propane-2,1-diyl)bis(2,4,6-trimethylbenzamide)

acetic acid

peracetic acid

2-iodoresorcinol

Downstream raw materials:

C₃₀H₃₅IN₂O₄

(S)-7,9-di-tert-butyl-1-oxaspiro[4.5]deca-7,9-diene-2,6-dione

N,N'-(2S,2'S)-2,2'-(2-iodo-1,3-phenylene)bis(oxy)bis(propane-2,1-diyl)bis(2,4,6-trimethylbenzamide)

Refernces

• 1、 Uyanik, Muhammet,Yasui, Takeshi,Ishihara, Kazuaki. "Hydrogen bonding and alcohol effects in asymmetric hypervalent iodine catalysis: Enantioselective oxidative dearomatization of phenols". supporting information. p. 9215 - 9218. Retrieved 2013/09/12.