BIS(DIMETHYLAMINO)-METHYLPHOSPHINE

Base Information

• Chemical Name: BIS(DIMETHYLAMINO)-METHYLPHOSPHINE
• CAS No.: 4534-85-4
• Molecular Formula: C9H23 N2 P
• Molecular Weight: 190.269
• Hs Code.: 2929909090
• Mol file: 4534-85-4.mol

Synonyms:Bis(diethylamino)methylphosphine;Methylphosphonous tetraethyldiamide

Chemical Property of BIS(DIMETHYLAMINO)-METHYLPHOSPHINE

Chemical Property:

• PSA: 20.07000
• LogP: 1.05130

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BIS(DIMETHYLAMINO)-METHYLPHOSPHINE

There total 5 articles about BIS(DIMETHYLAMINO)-METHYLPHOSPHINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

bis(diethylamino)chlorophosphine (685-83-6) + methyllithium (917-54-4) → bis(N,N-diethylamino)(methyl)phosphane (4534-85-4)

Guidance literature:

In diethyl ether; at -78 ℃; for 1h; Heating / reflux;

Reference yield: 36.0%

methylphosphonigsaurediethylamidchlorid (40467-94-5) + 1,4-bis(bromomagnesium)butane (23708-47-6) → bis(N,N-diethylamino)(methyl)phosphane (4534-85-4) + 1,4-Butandiylbis<(diethylamino)methylphosphan> (82159-36-2)

Guidance literature:

In tetrahydrofuran; 1,4-dioxane; pyridine; for 3h; Ambient temperature;

Reference yield:

methyldichlorophosphane (676-83-5) + diethylamine (109-89-7) → bis(N,N-diethylamino)(methyl)phosphane (4534-85-4)

Guidance literature:

In diethyl ether;

upstream raw materials:

methyldichlorophosphane

diethylamine

methyldibromophosphine

methylphosphonigsaurediethylamidchlorid

Downstream raw materials:

C₁₃H₂₀NO₃P

N,N,N',N'-Tetraethyl-P-(α,α,β-trichlorophenethyl)phosphonic diamide

2-methyl-3-phenyl-1,3,2-oxazaphospholidine

o-acetylphenyl N,N-diethyl-P-methylphosphonamidite

Refernces

• 1、 Den Heeten, Rene,Swennenhuis, Bert H. G.,Van Leeuwen, Piet W. N. M.,De Vries, Johannes G.,Kamer, Paul C. J.. "Parallel synthesis and screening of polymer-supported phosphorus- stereogenic aminophosphane-phosphite and -phosphinite ligands". supporting information; experimental part. p. 6602 - 6605. Retrieved 2009/03/12.