C₄₃H₅₈O₇

Base Information

• Chemical Name: C₄₃H₅₈O₇
• CAS No.: 1246949-33-6
• Molecular Formula: C₄₃H₅₈O₇
• Molecular Weight: 686.929
• Mol file: 1246949-33-6.mol

Synonyms:C₄₃H₅₈O₇

Chemical Property of C₄₃H₅₈O₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₃H₅₈O₇

There total 17 articles about C₄₃H₅₈O₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

C43H58O5 (1246949-32-5) → C43H58O7 (1246949-33-6)

Guidance literature:

With chromium(VI) oxide; sodium acetate; acetic anhydride; acetic acid; In water; at 0 ℃; for 0.666667h; Inert atmosphere;

DOI:10.1021/jo102054r

Reference yield:

C34H46O5 (1246949-45-0) → C43H58O7 (1246949-33-6)

Guidance literature:

Multi-step reaction with 4 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran / -10 °C / Inert atmosphere; Reflux

2.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 - 20 °C / Inert atmosphere

2.2: 0 °C / Inert atmosphere; Reflux

3.1: pyridine hydrochloride / 2 h / 135 °C / Inert atmosphere

4.1: chromium(VI) oxide; sodium acetate; acetic anhydride; acetic acid / water / 0.67 h / 0 °C / Inert atmosphere

With chromium(VI) oxide; lithium aluminium tetrahydride; sodium acetate; pyridine hydrochloride; acetic anhydride; sodium hydride; acetic acid; In tetrahydrofuran; water; mineral oil; 3.1: Marker's degradation;

DOI:10.1021/jo102054r

Reference yield:

3-OTBS-11-ketotigogenin (1246949-44-9) → C43H58O7 (1246949-33-6)

Guidance literature:

Multi-step reaction with 6 steps

1.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

2.1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

3.1: lithium aluminium tetrahydride / tetrahydrofuran / -10 °C / Inert atmosphere; Reflux

4.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 - 20 °C / Inert atmosphere

4.2: 0 °C / Inert atmosphere; Reflux

5.1: pyridine hydrochloride / 2 h / 135 °C / Inert atmosphere

6.1: chromium(VI) oxide; sodium acetate; acetic anhydride; acetic acid / water / 0.67 h / 0 °C / Inert atmosphere

With chromium(VI) oxide; lithium aluminium tetrahydride; di-isopropyl azodicarboxylate; tetrabutyl ammonium fluoride; sodium acetate; pyridine hydrochloride; acetic anhydride; sodium hydride; acetic acid; triphenylphosphine; In tetrahydrofuran; water; mineral oil; 2.1: Mitsunobu reaction / 5.1: Marker's degradation;

DOI:10.1021/jo102054r

upstream raw materials:

3-OTBS-11-ketotigogenin

C₃₄H₄₆O₅

C₄₁H₅₆O₄

C₄₃H₅₈O₅

Downstream raw materials:

(3α,5α,11β,16β)-3,11-bis(benzyloxy)-16-hydroxypregnan-20-one

C₄₇H₆₆O₆

(3α,5α,11β,17ξ,22S,24S)-3,11-bis(benzyloxy)-24-methyl-22,25-epoxyfurostan-20-ol

(3α,5α,11β)-3,11-bis(benzyloxy)pregn-16-en-20-one