Technology Process of (3R,5S)-5-(benzyloxy)oct-1-en-3-ol
There total 3 articles about (3R,5S)-5-(benzyloxy)oct-1-en-3-ol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
titanium(IV) isopropylate; L-(+)-diisopropyl tartrate; Cumene hydroperoxide;
In
dichloromethane;
at -20 - 0 ℃;
for 12h;
Inert atmosphere;
Molecular sieve;
DOI:10.1016/j.tetasy.2012.05.013
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: tetrahydrofuran / 1 h / -20 °C / Inert atmosphere
1.2: Inert atmosphere
2.1: titanium(IV) isopropylate; L-(+)-diisopropyl tartrate; Cumene hydroperoxide / dichloromethane / 12 h / -20 - 0 °C / Inert atmosphere; Molecular sieve
With
titanium(IV) isopropylate; L-(+)-diisopropyl tartrate; Cumene hydroperoxide;
In
tetrahydrofuran; dichloromethane;
2.1: Sharpless kinetic resolution;
DOI:10.1016/j.tetasy.2012.05.013
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 2,6-dimethylpyridine; sodium periodate; osmium(VIII) oxide / 1,4-dioxane; water; toluene / 4.5 h / 20 °C / Inert atmosphere
2.1: tetrahydrofuran / 1 h / -20 °C / Inert atmosphere
2.2: Inert atmosphere
3.1: titanium(IV) isopropylate; L-(+)-diisopropyl tartrate; Cumene hydroperoxide / dichloromethane / 12 h / -20 - 0 °C / Inert atmosphere; Molecular sieve
With
2,6-dimethylpyridine; titanium(IV) isopropylate; sodium periodate; osmium(VIII) oxide; L-(+)-diisopropyl tartrate; Cumene hydroperoxide;
In
tetrahydrofuran; 1,4-dioxane; dichloromethane; water; toluene;
3.1: Sharpless kinetic resolution;
DOI:10.1016/j.tetasy.2012.05.013
